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My blood test results. Are they in-line with LEF guidelines?

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 Posted 9/23/2013 5:09:16 PM
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Tom, I said low-dose Yohimbe; there are no side-effects with it--I've been taking it for many, many years and it works perfectly!
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 Posted 9/24/2013 8:33:47 AM
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Transpower - Even though it is well noted for its dose-dependent toxicity, there ARE case reports of side effects at low doses. Additionally, Yohimbine, even at low doses may act as an MAO inhibitor, thus preventing the metabolism of certain neurotransmitters like norepinephrine; a strong blood vessel constrictor. Tribulus is also a reversable MAO-A inhibitor.  The two compounds should not be combined, at lest not at the dose of tribulus I'm taking - dangerously low blood pressure, neurotoxicity among others could ensue. 

I've tried it at low dosages, alone and don't like its effects.

-Tom


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 Posted 9/25/2013 5:40:39 AM
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Tom, I do not take tribulus and do not recommend it.  Yohimbe does need to be combined with L-arginine and L-ornithine.  I love the effects of low-dose yohimbe!  My testosterone levels are excellent.
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 Posted 9/25/2013 8:03:15 AM
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Well, glad it works for you. It doesn't for me, and don't like the negative side effects. I don't recommend yohimbie.  

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 Posted 9/26/2013 3:38:14 AM
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Your experience with yohimbe is atypical, Tom.  For the vast majority of men it works very well, without side effects, which explains why it's such a popular supplement.
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 Posted 9/26/2013 2:25:57 PM
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Judging a supplements safety profile based upon its popularity is naive. 

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 Posted 9/27/2013 3:47:36 AM
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 Posted 9/27/2013 9:43:31 AM
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In young males with normal testosterone production some studies indicate it doesn’t demonstrate an increase. Clearly tribulus is working in some way via the hypothalamic–pituitary–gonadal axis (HPG axis), but it appears to work more as a type of adaptogen--balancing and restoring levels that are low rather than a flat-out increase as testosterone gel would do.


One problem when using herbs that have more than one effect is you don't know what is doing what to where and you risk invoking negative feedback due to what is doing what to where.  I have personally tried genuine Bulgarian Tribulus and there is a definite negative feedback mechanism in play after several weeks.  Given the information about its influence on LH that you posted, I now suspect that is the loop.  Any messing with LH will shut it down in the HPA axis and shrink your testicles.  Herb-hormonal interaction studies need to be long-term before declaring victory.  I advise sticking to single ingredients that target single pathways or enzymes.  It gives more flexiblity and less confusion when the whole enchilada stops working.  For example:

T (DHEA)
T<E1 (DIM)
T<SHBG (Nettle Root Extract)
T<DHT (Beta-Sistosterol)
T<LH (D-Aspartic Acid)

The rest of the HPA is good to monitor too because low thyroid causes high cholesterol and tumors in the adrenal or pituitary can effect the release of DHEA, HCG, melatonin, HGH, LH, FH or too much cortisol can gum up the whole works.  It's a real encyclopedia of interactions.

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 Posted 9/27/2013 9:48:54 AM
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Transpower (9/26/2013)
Your experience with yohimbe is atypical, Tom.  For the vast majority of men it works very well, without side effects, which explains why it's such a popular supplement.


Yohimbe just seems to be a herbal Viagra.  What evidence is there that it favorably modulates hormone levels as other proven supplements do?

Do you have excellent testosterone levels in the 500-900 range due to yohimbe?  What about your free T?
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 Posted 9/27/2013 9:28:32 PM
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Transpower is also taking DHEA and God knows what else.  IF his testosterone level is being modulated by his supplement use it is most likely the result of supplemental DHEA modulating the endogenous steroid hormone.

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