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Mitochondrial Energy Optimizer with BioPQQ

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 Posted 4/7/2013 7:32:52 AM
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I take Mitochondrial Energy Optimizer with BioPQQ.

According to you:

1) instead than taking 4 capsules a day, is it sufficient to take only 2 (one in the morning and one in the evening) o 3 caspsules (morning, lunch, dinner)?

2) How long has to be taken this product to be effective? When its anti-glycation effects are achieved?


3) Can it be taken all life long?

4) Are there any contraindication for long term intaking? 


Thank you!


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 Posted 4/7/2013 5:59:02 PM
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The recommended dose is two twice per day.  Since most of the ingredients aren't essential, one can't really say that a lower amount is insufficient.  In my opinion, two or three will still be of benefit.

The product should be taken indefinitely.

Although there are no warnings listed other than the standard ones (keep out of reach of children, consult with your physician if you are undergoing treatment for a medical condition, or are pregnant or lactating) there are some individuals who could develop a neuropathy from a high long term dose of vitamin B6, although it is rare.  Interestingly, not enough vitamin B6 can also cause nerve damage.  So if you are using vitamin B6 from other sources, you might want to cut your dose. 

Alpha-lipoic acid warrants the following warning: 

Because this product may lower blood glucose, consult your healthcare provider before taking this product if you are taking glucose lowering medication.

Concerning the other ingredients, anyone can have a sensitivity to any of them, or develop one, although that would be unusual. 


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 Posted 4/8/2013 10:51:23 AM
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It seems that the reommended daily amounts generally equals the amount to last one month. For example, if a bottle has 120 tablets, then the recommended dosage is would be four a day. There are of course exceptions to this rule. So, for most of the time, the suggested dosage has nothing to do with the user's health needs.
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 Posted 4/10/2013 10:56:40 AM
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I utilize Life Extension Mix that contains 105 mg of vitamin B6.
I also use Mitochondrial Energy Optimizer that contains 100 mg of vitamin B6.
Is 205 mg of vitamin B6 a too  high dosage for a long term taking?
What do you suggest?


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 Posted 4/11/2013 6:55:49 AM
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You say if we are getting B6 from other sources to cut our doage of MEO...but just about all of us take a daily multivitamin (such as LEF's 2-Per-Day) with B6.  Should we cut down our dosage of MEO to 2 or 3 per day?
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 Posted 4/14/2013 3:33:23 PM
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To rainbow, the amount of tablets or capsules in a bottle might be enough to last a month, but the dose is calculated with the needs of the majority in mind.

To Marco Santini, it is not possible to ascertain the precise amount of milligrams that could be problematic for one person and protective for another.  The incidence of vitamin B6-associated neuropathy is rare.  One physician recommended keeping one's dose below 50 milligrams per day; others are less conservative.

To Big Mike, my statement was:  "if you are using vitamin B6 from other sources, you might want to cut your dose."  This was in reply to his question concerning contraindications for long term use.  Very few people develop vitamin B6-associated neuropathy.  


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 Posted 4/22/2013 1:30:30 PM
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205MG a day is quite high but apparently not enough to do anything. . . 

"The FNB has established ULs for vitamin B6 that apply to both food and supplement intakes (Table 3) [1]. The FNB noted that although several reports show sensory neuropathy occurring at doses lower than 500 mg/day, studies in patients treated with vitamin B6 (average dose of 200 mg/day) for up to 5 years found no evidence of this effect. Based on limitations in the data on potential harms from long-term use, the FNB halved the dose used in these studies to establish a UL of 100 mg/day for adults. ULs are lower for children and adolescents based on body size. The ULs do not apply to individuals receiving vitamin B6 for medical treatment, but such individuals should be under the care of a physician."

To play it safe you should be around 100Mg a day.


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 Posted 4/22/2013 1:41:40 PM
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Welcome, Andy.

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 Posted 5/1/2013 5:22:45 AM
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I just saw MEO on the Overstock Sale.  Does this mean it is being reformulated?
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 Posted 5/1/2013 5:56:54 AM
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There were a couple of small changes.  Calcium increased to 253 milligrams and the content of the capsule itself changed to a chlorophyllin and vegetable cellulose capsule.   

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