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 Posted 1/22/2013 12:50:19 PM
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I work night shift and have been taking 20 mg daily, because it helps give me a good nights rest. Are there any dangers in taking this much long term? I've heard it lowers your natural production of melatonin, but doesn't melatonin production lower with aging anyway?
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 Posted 1/22/2013 1:26:15 PM
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Had not heard that it lowers your production, but endogenous melatonin production may decrease with age.  The only dangers known to me are:

1.  If one has an immune system cancer or autoimmune disease, melatonin could worsen it due to its stimulating effect on immunity.

2.  Driving or operating equipment after taking melatonin could be hazardous.

Higher doses are usually used by patients with nonimmune cancers.  Sometimes people who don't sleep well with the standard 1-3 milligram dose do better with lower doses such as 300-500 micrograms.


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 Posted 1/29/2013 1:03:46 PM
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triplecrown (1/22/2013)
I work night shift and have been taking 20 mg daily, because it helps give me a good nights rest. Are there any dangers in taking this much long term? I've heard it lowers your natural production of melatonin, but doesn't melatonin production lower with aging anyway?


Yeah, it does lower with aging due to calcification, and calcification is increased by fluoride in water and in toothpaste. You might try the time release version of melatonin and see if that doesn't work better for you.
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 Posted 1/31/2013 8:01:10 AM
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Thank DDYe and LouD,
I think I might give a time released version a shot Smile
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 Posted 3/21/2013 11:01:49 AM
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My mother has breast cancer and was put on ativan for calming and sleeping. She is 84 and the drug we believe caused her to have hallucinations and paranoia. What would be good for her to take to get a good night sleep? Can she take the melatonin but she has cancer?
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 Posted 3/21/2013 11:05:24 AM
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There is research to suggest that melatonin could help someone with breast cancer as well as with sleep.  See http://www.lef.org/protocols/cancer/breast_cancer_13.htm#treatment  But please consult with her physician first.

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 Posted 4/3/2013 5:41:03 PM
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triplecrown (1/22/2013)
I work night shift and have been taking 20 mg daily, because it helps give me a good nights rest. Are there any dangers in taking this much long term? I've heard it lowers your natural production of melatonin, but doesn't melatonin production lower with aging anyway?


No, " Regulation of melatonin secretion from the pineal gland does not appear to be negatively influenced by melatonin supplementation over the long term (multiple days) and no negative feedback from melatonin supplementation (less natural secretion after a period of supplementation) has been observed"

You can read more at Examine.com here: http://examine.com/supplements/Melatonin/
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 Posted 4/3/2013 6:28:45 PM
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Welcome to the Forums, Primalkid.

D Dye
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 Posted 4/5/2013 6:46:53 AM
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How did you choose 20 mg? Have you tried other amounts?Have you tried other LEF sleep aids?
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 Posted 4/13/2013 4:13:38 PM
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My understanding is as one ages their natural production declines, it is hormone and tolerances do develop.  I personally have been taking it for years and I find that it is best to calibrate the dosage.  Whatever amount I take, it makes me drowsy and  I fall asleep easy, but if I take too much I may wake up too early, and unable too fall back to sleep. So I always keep the dosage low and as my tolerance increases I increase the dosage. I always like take a break from it also. I have also read it is a powerful antioxidant, but I have no studies or research indicating that 
I have also read that it may be harmful if taken during the day and that it is best to be taken at night to match ones circadian rhthems.
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