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alpha-Tocopherol in Two-per-day

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 Posted 12/10/2012 7:41:33 AM
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Hi,

having read a LEF magazine article which strongly advises against isolated alpha-tocopherol without complementary gamma- and other tocopherols[1], I wonder why the Two-per-day contain only isolated alpha-tocopheryl succinate? I understand that LEF offers the Two-per-day for those who are on a tight budged or want to have their vitamins as convenient as possible, so this target audience is generally not to be expected to take the much more expensive (Super) Booster or the mixed tocopherol supplements additionally. Doesn't that mean that Two-per-day users are exposed to possible health risks, as stated by the article?

[1] http://www.lef.org/featured-articles/INFEML_Rebuttal_E_1018.htm
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 Posted 12/10/2012 9:06:05 AM
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Life Extension's Two-Per-Day formula is made with a minimum of dry ingredients so that people can get a formula that supplies the basics in as few tablets or capsules as possible.  Liquid compounds, including the tocopherols, can be added separately.  See http://www.lef.org/Vitamins-Supplements/Item00759/Gamma-E-Tocopherol-with-Sesame-Lignans.html

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 Posted 12/10/2012 9:42:58 AM
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Thank you for the quick response! It didn't answer my original question though. I know that you recomment to add mixed tocopherols, and I do, but I'm affraid that most people who take the Two-per-day (especially those who are not LEF members) neither know about this issue nor take additional Vitamin E. Those poeple shouldn't be exposed to a possible health risk by taking the Two-per-day.
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 Posted 12/11/2012 9:15:56 AM
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Product Development has informed me:  "As part of a future reformulation, we mayconsider adding the dry mixed tocopherols to our Two-Per-Day product."

The study in question used 400 mg alpha-tocopherol which is a higher amount than what is in the Two Per Day.  Nevertheless, Life Extension suggests adding the other tocopherols to any formula lacking them.


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 Posted 12/14/2012 10:56:03 AM
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That's good to know! They may be interested in this randomized human trial showing that a daily supplementation with a "low" dose of 200 IU alpha-Tocopherol lowered serum level of gamma-Tocopherol just as much as supplementaton with 800 IU did (see figure 1):

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688826/
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