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Big Calorie Cuts Don't Equal Longer Life, Study Suggests

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 Posted 9/1/2012 12:20:41 PM
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This looks bad news for extending life span but confirms health benefits and I am happy with that! Comments?

http://online.wsj.com/article/SB10000872396390444772804577619394017185860.html


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 Posted 9/11/2012 3:43:01 PM
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Don't we have any CR followers on this forum?  Will these results stop or slow their enthusiasm and converts?
Will the LEF CR mimetics be less popular?
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 Posted 9/11/2012 6:10:48 PM
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Full time CR?  To resemble a mummy in order to live longer? um…not for me. Infrequent CR days one can still look good, maintain visually pleasing body weight and still derive some benefit.  

Thanks for the info Albedo.


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The case against dietary fats >>  CLICK HERE
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 Posted 9/12/2012 3:46:33 AM
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Calorie restriction does decrease metabolic waste products, but these can be taken care of by supplementing with anti-oxidants.  The main problem, of course, is that it's necessary to take in natural compounds from the outside to make up for the reduction of production of these compounds internally as we age, and calorie restriction has nothing to do with that.
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 Posted 9/12/2012 4:34:57 AM
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The above linked study is one among many and is not finished because close to half of the animals are still alive, in whom an extension of MLS could still occur.  In studies with nonprimates, calorie restriction has extended LS in most species.  Even if it doesn't extend human life, its health benefits have been documented in several studies conducted among its adherents.  One can reduce calories without looking or feeling starved.  Roy Walford used to fast for entire days, and while some people can do this, others get hypoglycemia, which is damaging and dangerous.  Whether his ALS had anything to do with CR is unknown.  There are ways to cut calories and maintain blood sugar levels by consuming small, frequent meals.  If quality of life is impacted, then it's not worth it IMO.  By reduced QOL, am not referring to the loss of a bloating steak and lobster dinner with a baked potato and sour cream, and a small salad drowned in Roquefort dressing, followed by cheesecake.  What is meant is that if the diet causes hypoglycemia, headache, irritability, fatigue or depressed immunity, it may not be worth practicing. 

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 Posted 9/12/2012 11:58:37 PM
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DDye (9/12/2012)
There are ways to cut calories and maintain blood sugar levels by consuming small, frequent meals. 


This is one way in which micro greens can be used. On lower calorie days.


DDye (9/12/2012)
One can reduce calories without looking or feeling starved


I don't know … everyone that I've seen who does it religiously looks very gaunt. As they get older muscle loss becomes even more apparent.


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The case against dietary fats >>  CLICK HERE
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 Posted 9/13/2012 4:25:54 AM
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Tom. (9/13/2012)
DDye (9/12/2012)
There are ways to cut calories and maintain blood sugar levels by consuming small, frequent meals. 


This is one way in which micro greens can be used. On lower calorie days.


DDye (9/12/2012)
One can reduce calories without looking or feeling starved


I don't know … everyone that I've seen who does it religiously looks very gaunt. As they get older muscle loss becomes even more apparent.


Agree about the "gaunt" look.  I think the muscle-wasting results of a CR type diet can be overcome, however.  In the book "Nutrient Timing", muscle training and amino acid supplementation, specifically l-leceine(sp) will aide the body in increasing muscle mass much more effectively than weight training alone and would be an intelligent way to help prevent the "gaunt look".   
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 Posted 10/4/2012 8:01:38 AM
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I thought this case was somewhat interesting in relation to this thread.

"On Thursday, Paulding County Sheriff's Detective Kevin Morgan testified that the teen was so small and slight, Morgan thought the boy was 12 years old. He added that Comer was so malnourished, he still had baby teeth at age 18."

It sounds like the abuse had to have started well before 8th grade (14 years old) to still have baby teeth, if it was due to malnourishment.

http://www.11alive.com/News/Crime/259482/445/Parents-accused-of-locking-son-up-now-seek-bond
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 Posted 10/5/2012 6:15:46 AM
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Is calorie restriction really IRON restriction in disguise?  

Calorie restriction should result in lower iron intake and age related iron build-up, but if foods are fortified with iron, or iron is supplemented to compensate for reduced iron in the diet, this could be a confounding factor that might explain why different CR studies produce different results.  

Can Humans Live Longer? http://www.lewrockwell.com/orig/sardi10.html  (by Bill Sardi)

Calorie or iron restriction?

Researchers at the University of Texas Health Science Center in San Antonio, Texas, measured the aging rate of mice at 6, 12 and 24 months by determining the level of oxidation (rusting of tissues) in various organs. The more food these animals consumed the more iron that accumulated in their tissues and the greater the oxidation (aging). As early as 1985 researchers proposed that the rate of age-related iron accumulation correlates with the life span of some species. The accumulation of iron in these rodents did not occur till growth had been completed. After that time iron levels increased in the liver by 140 percent and the kidney by 44 percent. The liver and brain experience the greatest iron buildup with advancing age. An iron-restricted diet minimized the oxidation levels in the liver, kidney and brain with advancing age.


The lifespan of the fruit fly has been found to be proportional to the iron content in the diet.  

Excessive iron has been found to be the initiator of aging in fruit flies.



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 Posted 10/5/2012 6:35:24 AM
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Interesting.  Hypotheses have also been submitted that methionine or tryptophan restriction could be the beneficial factor in calorie restriction. Protein restriction has been hypothesized as well.
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