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High PSA (6.75) - want testosterone replacement anyway

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 Posted 1/9/2011 7:11:50 AM
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JanSZ - Thank you. I'll check into that after I see what my results are after trying everything listed. I go in on the 19th of this month and it'll take a few days to get the results back. Pete

*Also, "thank you's" to albedo, guizi and itsallabouthealth - looks like I've got a lot more reading/experimenting to do!

In the meantime, an interesting article:
http://www.healthiertalk.com/lower-psa-pomegranate-3112

Lower PSA with Pomegranate

"Now, a clinical trial shows that lowering levels might be as easy as drinking a glass of pomegranate juice . . .

 . . . Look for a supplement made from a whole-food source and take 500 to 1,000 mg. daily. It’s an easy way to do something nice for your overall health—and especially your prostate."

References:

Bell C. Ellagic acid, pomegranate and prostate cancer -- a mini review. Journal of Pharmacy and Pharmacology. 2008;60(2):139-144.

Malik A. Pomegranate fruit juice for chemoprevention and chemotherapy of prostate cancer. Proceedings of the National Academy of Sciences USA. 2005;102(41):14813-14818.

Pantuck AJ. Phase II study of pomegranate juice for men with rising prostate-specific antigen following surgery or radiation for prostate cancer. Clinical Cancer Research. 2006;12(13):4018-4026."


"Be polite, be professional, but always have a plan to kill everyone you meet."
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 Posted 1/9/2011 5:30:58 PM
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Indicator1 (1/8/2011)
Tom,

Well, I want to lower or eliminate foods and supplements that can increase IGF1.

Do you have a list of them? Your link does not give any idea...

Thank you.

Indicator1


Here are a few that I know of:

Caffeine
Dairy
High protein diets
Whey protein
Colostrum
Bovine plasma protein
High amounts of glycine, proline, glutamine
Creatine

Keep in mind that increasing IGF-1 or growth hormone levels has shown some therapeutic benefits.  I'm  not sure where the line is indicating too much.  My opinion is if a person has high PSA levels, a personal history or family history of cancer it would probably be prudent to minimize substances that increase growth hormone. For this reason my opinion is that growth hormone used in HRT should always be under a doctors supervision.


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 Posted 2/15/2011 2:06:03 AM
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I turn 70 this year and have had a decades long history of BPH and consequently a consistently high PSA.  Over the last decade it has varied from 4 to 10, staying mostly around 7.   When my Total Testosterone came in at less than 200 six years ago and was repeatedly measured at 175 to 185 two years ago I asked my docs for test supplementation.  They were satisfied that my Biopsy from almost 10 years ago was good and my PCA3 test from '06 was also excellent then they supplemented them with a test of my PSAF.  My percentage here was also excellent at 24.9 so they were convinced that my high PSA was a result of my BPH and not Cancer and made a plan to slowly ease me into TRT.  For the first 6 months they had me on the patch at only 2.5 mg ED.   We have now gone on to using Test Cyp injections 1 X wk at first 100 and now 200 mg.   My test rose slowly into the 300s on the patch, then to the 400s and finally it has steadied out in the 900s.  All of my negative symptoms from the low test have now disappeared ED, depression, sleeping etc.   My Urologist and I monitor my test and PSA levels at least monthly, meet regularly and are ready to adjust as needed.  If after a year it continues steady we will then stretch out the test periods until they are eventually every 6 months.  

When my PSA first reached 10 while living in Holland I was fortunate that they took an entirely different approach then in the US.  They did the biopsy and simply put me on Saw Palmetto, Pygeum and Pumpkin Seed.  Nowadays I use instead Beta-Sitosterol, Milk Thistle and Stinging Nettle Leaf (which also helps my free test).  I learned that not only sexual activity but strenuous exercise (running or gym) also affect my PSA and the levels can rise several points as a result.  I should add that my Urologist and I placed a lot of weight on the latest info which showed that high test levels corrolate well to low prostate cancer levels.  As a true vitamin junkie I also megadose my D3 to keep my level around 70 ng/dl and Omega 3s between 2.5 and 3.0 gms.  I also take my Curcumin, Broccoli Extract and Selenium as part of my Ca protection plan.  Hope this example and info is of some help.
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 Posted 2/15/2011 7:45:34 AM
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Great post Pokebu, thank you for sharing this very valuable information. I am also getting good results with the very same natural supplementation as your and tamsulosin for mild BPH. When comparing to those results I wish to report my PVR (Post Void Residual) has also improved in my last (Dec 2010) test. I also increased beta sitosterol intake.

Just curious to know if you also touched DHEA.
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 Posted 2/26/2011 9:37:18 AM
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Just as an update, I go in for my next test on Mar. 4. (I missed the one for this month due to work demands).

albedo - How much beta sitosterol are you actually taking now?  I'm taking 375MG x1; nettle root extract (500MG x2); Lyc-O-Mato 40MG x1; saw palmetto extract 320MG x2; Uniflora's Propolis Extract (Strong Type) 15 drops x2;  and LE's pomegranate extract 1OZ. x1.

Subjectively, things are going a LOT better, prostate-wise - I'll know the numbers after the appt. Pete


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 Posted 2/27/2011 1:59:08 AM
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spy1 (2/26/2011)
...albedo - How much beta sitosterol are you actually taking now?  ...



I have added an average (not regular intake) of ~110mg / day. This is in addition to the beta sitosterol content of the full dose LEF formula. No effect on libido at there relatively low doses. As I guess I mentioned elsewhere I added a bit more Lycopene, Quercetin, reduced doses of Zyflamend, Selenium, Curcumin, IP6/inositol, Zinc, Pumpkin Seed Oil, EPA/DHA, pomegranate extract.  I regularly eat soy products as tofu (for isoflavones) and broccoli (for I3C). I am probably forgetting other components but I guess it is all a matter of synergy and not overdosing with anything, even "natural". My only medication for mild BPH is tamsulosin (~0.2 mg/d). So far so good ...
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 Posted 3/14/2011 8:35:00 AM
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Well, the PSA test results came back - 9+ if you can believe that.

He still wants to do a biopsy (which would be my second one), but I'm not having it done anytime soon.

What I have done is added green tea extract to the mix (2 per day) -

stopped
taking the DIM-Plus I was taking -

cut back on the amount of saw palmetto extract I was taking ( to 320 instead of 640mg, although I am still taking the separate 375mg Beta Sitosterol tablet - just taking them 12-hours apart instead of together) -

doubled up on my zinc/copper intake (from 30+2 to 60+4mg, 12 hours apart) -

and doubled up on the Lyc-O-Mato (likewise 12 hours apart).

I also just re-ordered from LE the PectaSol-C MCP ( 00342) - the pomegranate juice concentrate ( 00957 ) and the water soluble pumpkin seed extract ( 01209 ).

Also, I'd like some input from anyone who has tried Prostabel ( http://www.natural-source.com/engl/prostabel.php ), if anyone, because that stuff's horribly expensive and I'd hate to divert funds to something I just heard about when there are so many other things I could use the money for.

I'm still very upbeat about all of this, BTW and intend to handle it "naturally" if at all possible. Pete


"Be polite, be professional, but always have a plan to kill everyone you meet."
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 Posted 3/14/2011 8:40:56 AM
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What is your age, if you don't mind me asking?
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 Posted 3/14/2011 9:00:18 AM
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I'm 59 - I'll be 60 at the end of October.

"Be polite, be professional, but always have a plan to kill everyone you meet."
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 Posted 3/14/2011 9:23:37 AM
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Would undergo the second biopsy if it were me.

A relative of mine was diagnosed with PC in his 50s a couple of years ago.  It was a very aggressive variety but he waited a few months to qualify for an endoscopic prostatectomy.  The doctor got everything, despite the wait on my relative's part.  He's fine now.
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