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PQQ and Mitochondrial bio-genesis questions?

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 Posted 2/2/2011 12:10:51 PM
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Interesting discussion! I exercise a lot and that should induce mitochondrial biogenesis. Is there any benefit for individuals who do a lot of exercising to take PQQ supplements or can it be even harmful?
Post #1273
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 Posted 2/3/2011 3:44:48 AM
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Keep in mind that it is STRENOUS resistance exercises and aerobic exercises that stimulate mitochondrial biogenesis. Think of it this way, even if you exercise a lot, PQQ may help to enhance your exercise efforts.

Michael A. Smith, MD
Clinical Information Specialist
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 Posted 2/8/2011 11:18:04 AM
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syntax (2/8/2011)
Hello Albedo, Reading your posting about quercetin reminded me of a discussion in the old forum about QUERCETIN used in combination with ultra sound as a very effective treatment for PROSTRATE CANCER. Here is a British Journal of Cancer article that discusses this treatment:   http://www.nature.com/bjc/journal/v92/n3/abs/6602364a.html

And, here is a link to an informative discussion in " the old forum " about this topic: http://forum.lef.org/default.aspx?f=41&m=49931


Thank you Syntax you brought this up again! Such a good information! I completely overlooked it. Quercetin is known for prostate conditions and combination with ultrasound looks interesting and worth trying. Keep posting this sort of information.


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 Posted 2/8/2011 8:00:49 PM
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Thank you all, indeed! I love it when I find out that something I'm taking for something entirely different turns out to be good for something else.

Gotta love it. At least now I don't feel like I totally wasted my money on the quercetin. Pete


"Be polite, be professional, but always have a plan to kill everyone you meet."
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 Posted 2/13/2011 9:04:10 AM
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One question I have about the PQQ is whether someone must continue to take it. If it does restart and increase the mitochondria, then once the population number is increased, will I only need to keep them fed with something like CQ10? If the reduced number is simply the result of aging, in that they are lost after so many divisions, then once the number is increased or restored do I need to continue the PQQ? The supplement would be fairly expensive to continue to use for years and years. Using it for two or three months to get numbers back up would be a different consideration.
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 Posted 2/14/2011 4:18:56 AM
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Yes, one should continue to use the product.

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 Posted 2/17/2011 12:39:22 AM
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Is it possible to use PQQ for nasal administration?  It is water soluble (sodium salt), hardy cross BBB, has no adverse effects, works very quick in vitro, but slow invivo (brain). The capsule contains only rice flour and PQQ... Real temptation...

I'm with Parkinson's.



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 Posted 2/17/2011 4:09:01 AM
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Am not aware of any research that has been done concerning this route of administration, so will not recommend it.
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 Posted 2/18/2011 2:54:02 AM
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rasarver (2/13/2011)
One question I have about the PQQ is whether someone must continue to take it. If it does restart and increase the mitochondria, then once the population number is increased, will I only need to keep them fed with something like CQ10? If the reduced number is simply the result of aging, in that they are lost after so many divisions, then once the number is increased or restored do I need to continue the PQQ? The supplement would be fairly expensive to continue to use for years and years. Using it for two or three months to get numbers back up would be a different consideration.


I think this is a good question. Too many mitochondria is known to spur cell division, as in ashma, for instance. In my case, I'm noticing muscles that I haven't seen in ten years. Perhaps a year down the road I will switch to less than daily use (or to the formulation with only 2.5 mg per cap), but right now I see no negatives.
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 Posted 2/25/2011 3:34:19 PM
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Are you saying that plain PQQ might not be safe unless taken with other things or that it is unsafe with vitamin C? This is very confusing.  The article in the LEF magazine did not  elude to any problems that could come from taking PQQ.
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