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PQQ and Mitochondrial bio-genesis questions?

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 Posted 1/17/2012 5:18:51 AM
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I seem to get energy from the new Magnesium product from LEF though I had been taken the other one they have.  My best bang seems to come from ALA with ALCAR that has a little biotin. It makes me into a more energetic 71 year old so that I can keep on dancing the night away.
Post #4859
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 Posted 2/2/2012 3:42:04 PM
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i read that PQQ causes increase in cAMP .

Some other substances which raises cAMP (Forskolin, etc) can increase cancer's metastasis.

Should i feel any safer with PQQ ?


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 Posted 2/3/2012 12:43:54 PM
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Good question Evermore...

I too would like to know whether PQQ is safe in this regard?
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 Posted 2/3/2012 1:18:33 PM
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Have forwarded this to advisory@lifeextension.com and am awaiting a reply.

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 Posted 2/6/2012 5:33:39 AM
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From the advisory department:

We have notseen any indication that PQQ promotes cancer. Due to its powerful antioxidantproperties, we suspect that is may help to protect against unhealthy cellgrowths.

Research about PQQ and cancer is still in its infancy. However, we were able tolocate studies showing that the nutrient inhibited melanin synthesis incultured melanoma cells and protected neuroblastoma cells from the damagenormally induced by the neurotoxin 6-hydroxydopamine (6-OHDA). These studiessuggest that PQQ may minimize the cellular damage that can lead to mutations.DNA mutations are often the starting points for cancer growth. Here are linksto these two studies:

http://www.ncbi.nlm.nih.gov/pubmed/19013771

http://www.ncbi.nlm.nih.gov/pubmed/17268846




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 Posted 4/4/2012 11:26:42 AM
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DDye (12/19/2011)
These nutrients can be consumed during colds or influenza.
I was taking 10mg a day (Mitochondrial energy optimizer) and I got a cold four times.. Not sure if it was related to the PQQ somehow. I stopped the PQQ and didn't get the cold again. Could the cold be a mitochondrial side effect as in overdoing it somehow? I was exercising too when I didn't have the cold. My diet is usually a low carb one which I've just read can trigger mitochondrial biogenesis too.....

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 Posted 4/4/2012 11:29:50 AM
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It is likely a coincidence.
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 Posted 4/4/2012 11:30:14 AM
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What I've noticed after my usage of PQQ is that some hair loss I had seems to have reversed itself. I do have some new grey hairs however.
Also I lose weight more easily now. Even if I eat food which used to make me gain weight, I will stay the same weight or even lose some.. 
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 Posted 4/4/2012 11:48:27 AM
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DDye (4/4/2012)
It is likely a coincidence.
Well, I usually never get 4 colds in winter.. it was really unusual.
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 Posted 4/4/2012 11:52:27 AM
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Have you had your serum vitamin D level tested?

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