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Glucophage (Metformin) Prescription?

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 Posted 1/29/2012 4:38:57 PM
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The physician's prescribing information for metformin states:

"Hypoglycemia does not occur in patients receiving Metformin alone under usual circumstances of use, but could occur when caloric intake is deficient, when strenuous exercise is not compensated by caloric supplementation, or during concomitant use with other glucose-lowering agents (such as sulfonylureas and insulin) or ethanol.

Elderly, debilitated, or malnourished patients, and those with adrenal or pituitary insufficiency or alcohol intoxication are particularly susceptible to hypoglycemic effects. Hypoglycemia may be difficult to recognize in the elderly, and in people who are taking beta-adrenergic blocking drugs."

The information states that metformin doesn't cause hypoglycemia in type 2 diabetics and normal individuals except in special circumstances (above).  It doesn't mention those who are chronic hypoglycemics. 


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 Posted 1/29/2012 4:56:32 PM
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To Rainbow and Coochie, although many drugs have unwanted effects, "natural products" may as well in some cases.  Additionally, they may not be able to accomplish what drugs can.  We are looking at extending human life span and lengthening the healthy portion of life, and that may not be possible with nutrients alone, although they certainly play a role.  Furthermore high dose nutritional supplements also supply to the body what the diet never would, and are, in this sense, not "natural." 

Still, my recommendation is to supplement with vitamins, minerals, amino acids and compounds that are needed by the body, whenever possible. 


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 Posted 1/30/2012 4:12:12 AM
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I do not believe everything in the PDR either. Metformin will not cause hypoglycemia if used properly then. It is the only drug indicated for impaired glucose tolerence. In IGT patients, they  may have normal fasting sugars and therefore oral hypoglymics would case low sugar, not so with metformin. If metformin is used in the elderly it builds up because of renal insufficiency or interactions with other meds and therefore should be avoided. Similar to patients that are dehydrated or ill. Of course metformin could be associated with hypoglycemia when used with other diabetic meds. In fact metformin will delay outright diabetes in partients with impaired glucose tolerance. I did not read LEF article mentioning metformin but I would think the jest was to say that most people should have improved glucose tolerence.  BTW Danya your posts are the most informative and of course you can only rec. supplements.
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 Posted 5/19/2012 4:02:19 PM
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I was diagnosed a diabetic over 20 yr ago but it was too mild for my docs to prescribe metformin.  I wanted it so I bought it on the internet.  When my doc found out she was angry but finally consented to prescribe it.  So far my A1C has never hit the 6s.

There has been some concern that metformin may spur Alzheimer's Disease.
http://www.youtube.com/watch?feature=player_embedded&v=TuKMZVbB5ww#!
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 Posted 6/27/2012 3:38:42 PM
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You have to find a doctor that will prescribe Metforin for you. Try to find a doctor that practices Alternative or Functional medicine and is also a Alopathic Physician. Metformin is on the Walmart Pharmacy $4.00 list in my area. Just $4.00 For a 30 day supply. I am in Phoenix, AZ
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 Posted 6/28/2012 1:37:32 PM
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Any suggestions on how to reduce GI side effects?  Also, a 50+  diabetic lady friend did get dangerously low blood sugar at times while using metformin.  If I take it I will always carry glucose tablets just in case I feel faint.

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 Posted 7/7/2012 12:32:41 AM
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My fairly conservative endocrinologist prescribed metformin for me when my FBG was under 100.  And it was his idea.

His idea was to use it to treat "insulin resistance", some formula that is a function of your FBG measurement and your insulin measurement, measured at the same time.  (I thought he said it was a function of insulin/FBG, but a quick internet search seems to show that it's a function of insulin x FBG.  Either way, higher insulin => more insulin resistance.)

Measuring my insulin was also his idea.  But maybe it would work for you to ask your MD  for an insulin test along with your next lab FBG, and if the insulin is elevated, then ask for metformin to treat the insulin resistance.

(Also, he did warn me that some people feel cruddy on metformin and some people feel better, and that we should stop it if it was the former.  No surprise there.  It's a drug, of course it can have negative effects for some people.)
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 Posted 7/8/2012 11:56:45 AM
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Welcome to the Forums, Mario.

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 Posted 7/10/2012 6:11:53 AM
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any melanoma pts on metformin? tested for BRAF V600E mutation? Added VEGF's?

what about pts who had successful [?] excision of low stage melanoma? potential to enhance silent metastasis?


ok to respond directly [preferred]: icf@cds1.net

thanks, Richard

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 Posted 7/15/2012 6:09:31 AM
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My Mom is a Type2 and was put on Metformin several years ago at a really high starting dose. It made her very sick and they took her off it. And put her on rotating collection of medicines that she could never stay on.. nothing ever evened out.

Near desperation she decided to ask to go back on Metformin and slowly work up to the prescribed dosage over about three weeks. She watches her blood sugar very carefully and watched it come down.

Its been very effective and useful for her ever since. The gastric problems did not return and she's happy with it.

It looks like it works, if you ease into it and don't expect immediate results and give the body a chance to get use to it.



 
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