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Glucophage (Metformin) Prescription?

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 Posted 1/27/2012 11:54:39 AM
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The Feb 2012 LEF Magazine states at the top (and within) that Metformin is "A prescription drug virtually everyone needs".  The question I have is how do you get a doctor to prescribe it if you are not diabetic? I have been checking my FBG every morning for the past 3 years and I avg between 100-108. Last lab work at the primary care doctor it was 102.  I am exercising, changed to a Paleo diet, take various supplements for BG and all this helps, but I would really love to get on Metformin to help me get down into the 80s and for the potential added cancer risk reduction.  My current doctor will not prescribe it. The find a doctor list here on LEF.org may be of use but so far they all over 50 miles away, are not "in-network" for my Cigna insurance, and many are not taking new patients. Sad

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 Posted 1/27/2012 12:05:40 PM
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Perhaps you could show the article to another physician, such as an endocrinologist.

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 Posted 1/27/2012 1:01:55 PM
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Don't believe everything you read in LEF. Metformin is a DRUG and is indicated only in AODM and in those patients who have impaired glucose tolerance. If your doctor says no, he is proably correct with your sugars (you would need a glucose tolerance test or Hbac1 to be abs. sure about impared glucose tolerance). In fact if he did prescibe it, he would be consider negligent if any side effects would occur. If you want a good supplement for glucose utilization try psterostilbene 50 mg BID. My infor is solid, GL.
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 Posted 1/27/2012 1:21:42 PM
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My fasting blood sugar is a little high (around 90) so I tried metformin starting with a low dose.  My body rejected it.   My stomach and intestines took an immediate dislike and I had pretty much every possible side effect listed.   Additionally, my regularity that you could set a clock to was totally gone.   I felt horrible.  Note that I am not overweight and don't eat many 'empty' calories.   I will continue to look for ways to get that fasting blood sugar number down but no way will I take metformin ever again.   I personally think LEF should be more careful about recommending something for everyone, particularly something that had such an adverse effect as it did on me.
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 Posted 1/27/2012 1:32:52 PM
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The above comments will be forwarded to Life Extension Magazine for their consideration.

Metformin is not used by some people because of hypoglycemia, and there are others for whom the drug is contraindicated. 


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 Posted 1/27/2012 1:48:01 PM
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coochie,

LEF was the LAST place I heard about the added benefits of Glucophage.  Many of the CR sites talk about it, and I've seen articles and more than a few studies on other sites about potential lower risk of cancer.  On the down side, I've read the potential for lower T, lower folate and B12, and raised homocysteine and TNF-alpha.

But I do know it works for me. I was paying IAS for it for 9 months and my BG numbers dropped and my HbA1c went from 5.4% to 4.8%. Its just pretty expensive that way.

And yes I'm taking
psterostilbene from biotivia's pteromax and recently bought some from Genceutic Naturals. Of course there is a very sparse amount in LEF's CR Mimetic too, but its way too costly for the 3mg (even with the other ingredients).

With this,  the ALA, the GSE, corosolic acid, cinnamon extract, etc. and of course diet and exercise I'm almost able to maintain my numbers, but last HbA1c was back to 5.1%

Yes Metformin is a DRUG... but that in it self makes it no more harmful than an herb such as G. officinalis (Professor weed) for which shares its effects. At the moment the positives for it seem to outweigh the negatives from my POV given the high incidence of lung cancer in my non-smoking family.
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 Posted 1/27/2012 4:29:52 PM
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Gerry, Btw metformin does not cause (symptomatic hypoglycemia).  Most people would be very happy with a a1c of 5.4. I do believe in low a1cs but at what expense or effort? My best a1c was 4.7 but I use short acting insulin before high glycemic meals-pasta. I avoid bread, sugars and other high glycemic carbs but love pasta. Fast acting insulins (or exercise after such meals) are the ticket to prevent even minor funcs. in high sugars (over 120). I still use 5-7 units of insulin (Humalog) before such meals but would caution against drugs (exogenous small doses of Humalog or Novolog I feel is safe and at such a small dose is not a drug). Or best yet go for a walk after high carb meals. FBS of 70-80 are unusual and I feel not necessary to maintain a a1c below 5. (Lef does sell a 50 mg pstero. and why they put 3mg in their CR is beyond me) As an MD I have no problem getting meds and cannot treat patients like I treat myself (prescribe insulin or diabetic drugs to non-diabetics).
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 Posted 1/27/2012 8:22:39 PM
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coochie,

I didn't mention hypoglycemia... you must be confusing my post with the moderators. And no I'm not happy with a 5.4 or 5.1 A1c. My wife and I walk after meals, and I do HIT 3 times a week and fairly lean and muscular. The added muscle did help with the insulin sensitivity. And your mention of augmenting with fast acting insulin to drop postprandial BG... I have done this (and I know people that still do this that also take HGH which I do not)  but with my current diet, postprandial numbers do not spike (because I don't eat the junk you refer to) plus insulin is a double edged sword. My effort is to find the best way to: have lower BG, lower insulin, lower IGF1, improve insulin sensitivity, and minimize endogenous AGEs and ALEs via meal combinations/timing and taking a few sups to reduce glycation AND lastly decrease my chance of cancer (which is high in my family). I do see Metformin fitting in this plan (and have used it successfully). If you do not like the idea then by all means do not take it.
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 Posted 1/27/2012 10:15:28 PM
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 Posted 1/28/2012 6:55:57 AM
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It always upsets me whenever LEF suggests anything that is not natural like drugs.

It  seems like the easy way out to reach for a drug. Just experiment more with LEF products or other company's products  to find a solution.
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