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Has LEF Mix been updated?

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 Posted 11/11/2011 10:03:32 AM
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It is due to increased demand.
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 Posted 11/15/2011 4:21:13 PM
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That's pretty incredible, really speaks to the ability of supplements to appeal to the human existential condition, since I am assuming that vitamin E (as one of the most basic and oldest supplements) has a robust manufacturing infrastructure in place for its production.  It's particularly interesting that there is a global shortage of the vitamin since studies on the efficacy of E for improving human health are far from definitive.

I need to find ways to invest in the supplement industry!  Perhaps we should start a forum on publicly traded stocks options that derive revenue from supplements. 
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 Posted 11/16/2011 4:16:09 AM
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You could certainly start a thread and if it were well trafficked, a forum might be in order.
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 Posted 12/13/2011 11:17:28 AM
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  My brother had mentioned a problem with stomach upset when first taking the Two-Per-Day tablets with a few other supplements on an empty stomach.  Since this was my brothers supplements I don't have the batch number.  He adjusted his schedule to take Two-Per-Day tablets with food and to spread his supplement times out and hasn't mentioned a problem since.  So it probably wasn't a batch related problem - just a sensitive stomach issue that's no longer a problem.

  I did order the Two-Per-Day Capsules for my mom - she prefers supplements in capsule form - and they do seem to have less odor than the tablets.  I am also recommending the capsules to my brother, since he would benefit from the better form of Vitamin D and the addition of Alpha Lipoic Acid - neither of which he gets from other supplements.  My mom does already get these enhanced ingredients from other supplements, but the additional Alpha Lipoic Acid will be beneficial for her diabetes and the enhanced Vitamin D may allow her to eliminate her seperate Vitamin D supplement.  The lower Vitaman E dosage is a reasonable tradeoff since she gets additional mixed forms of Vitamin E from the LE Super Booster.
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 Posted 12/17/2011 5:23:55 AM
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Rob9737 (11/9/2011)
That's really interesting: I am guessing that so many people in the world are taking Vitamin E that there is a global shortage?  Or is there some other factor at play? 


Found it rather funny to speak about a global shortage of alpha-tocopherol. A shortage implies that customer demand is larger than the supply and therefore a higher price. But if I compare the price of alpha-tocopherol with the one for mixed tocopherol or tocotrienols the shortage seems rather in the later compounds, really.

Also locally, where I live in central Europe, mixed tocopherols or trienols aren't even available regularly in supplements shops, unless ordered from oversees at outrageous prices. While alpha-tocotrienols can be bought at every supermarket, and that very cheap for many years. So suspect that it's the LEF's preferred succinate form of vitamin E, where the supplies haven't met the customers demand.

However, I actually love the massive decrease of vitamin E with the latest LEF Mix formula, which allows me to use up my own overstocks on vitamin E (due to its easiest availability, cheapest price and my decreasing ignorance) and get a more healthy balanced intake of all vitamin E isomers.

Actually just ordered the full dose of a years supply of LEF's mix powder, instead of only using a partial dose as the years before while adding many helpful nutrients individually, which in the long run was just to impractical. For my needs LEF's mix powder comes closed to perfect - and I really love it for that.

But for to being really perfect multi, with the understanding that it's formulation is constantly reevaluated and improve upon, I also would like to add my own suggestions and questions here:

  1. First of all, for me it seems the powder form is the most preferential, because it avoids all the usual but unnecessary fillers in capsules or tablets, which I already get a big share of from my extensive supplement regime (I use successfully against a serious PAD). But since I also avoid any sugar I really would prefer it without any of the presently added maltodextrin. Is this really a necessary addition, or couldn't it replaced with something without any harm at all? I calculated all active nutrients to make up 8.4 of the 12 grams daily dose for this multi. From the remaining 2.6 gram I would reckon the maltodextrin not taking up much more than half, which certainly is really a tiny amount with little concern. Still I would view that tiny amount of fast acting sugar completely wrongly placed.
  2. But still the biggest flaw of LEF's mix is the massive amount of 335,96 mg magnesium oxide, the least absorbable form for this critical mineral where deficiency is very widespread and where I personally need about 1 gram to avoid painful muscle cramps in their best available forms (malate, glycinate, citrate..), where magnesium oxide simply doesn't contributes anything for me. Of course, I'm aware that these better absorbable forms would take up too much volume in tablets or caps and oxide is still better than nothing for most customer, but in LEF's mix powder volume wouldn't pose an issue and could at least be implemented here to give customers a much better choice. I believe the increased sales of LEF's mix in such an improved formula would certainly reflect.
  3. One question is about 'ion exchange resin' listed as a for of vitamin B12 in the ingredients list. Could someone enlighten me how this came to be listed as vitamin B12? Because wikipedia only mentions: 'Ion-exchange resins are also used as excipients in pharmaceutical formulations such as tablets, capsules, and suspensions. In these uses the ion-exchange resin can have several different functions, including taste-masking, extended release, tablet disintegration, and improving the chemical stability of the active ingredients.' Is anyone aware other sources for listing 'ion exchange resin' as vitamin B12?
  4. Next, why such a high amount of chromium. Is the used Chrominex so much less bio-available?
  5. Why not add at least 99 mg of potassium? An other very widespread deficiency and where I personally need supplementation close to the gram range to remedy it's grossest deficiency, as shown in my serum and hair mineral tests.
  6. An other big issue I see is that a large percentage of the population aren't able to convert carotenes to active vitamin A. I therefore think a larger percentage than the 10% retinol present in LEF's mix would be appropriate to give biggest benefit to most. Though I consider it only a minor issue, but what could be causing concerns to now health-conscious but formerly tobacco smoker, are the remaining 90% of carotenes. To put this into perspective with studies which found a small disadvantage with high dose beta-carotene in former smokers, does anyone know how the 5000 IU vitamin A breakdown into 10% preformed and 90% carotenes comes to in actual milligrams each? (there are different calculations: from 2mg of beta-carotene in oil to 12mg from diet equaling 3.33 IU vitamin A, which both doesn't applies to LEF mix)
  7. But when it comes to fat-soluble nutrients I consider most of them completely misplaced in dry powder, caps or tabs anyway, and I haven't found anything other than very imperfect multies in this respect. For example: I need double the amount of vitamin D3 in dry form, than I would need in softgels to reach equal serum levels of 25(OH)D3. What a waste! Next they are partially inhibiting each others absorptions, for example when I raised my vitamin A to vitamin D ratio above 8 : 1 taken separately (ie. more than 1600mcg A with 200mcg D3) my serum vitamin D3 halved, and doubled again by reverting to my former ratio. Also the expensive tocotrienols should be taken separate from mixed tocopherols for better absorbtion. And a possibly diminishing serum vitamin K level with sole alpha-tocopherol supplementation alone, as with LEF mix formula, would be an other good reason to stay with the presently 100 IU of vitamin E in future formulations too. Instead spend more brain-power on a really good combination of all fat-soluble nutrients  - best in two distinct softgels - where tocotrienols are separated from tocopherols, preformed vitamin A from D3, and xanthophylls like lycopene or astaxanthin from each other too. For which LEF instantly certainly would not only win me as a regular customer for such a new multi, with 2 distinct softgels for all fat-solubles.
All for now, and please don't be put off by my many concerns, I still consider LEF mix powder the multi comes closest to perfect Wink

Thanks for considering and any answers in advance.

Post #4547
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 Posted 12/19/2011 5:01:11 AM
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What is the best way to take your LEF Mix?

Plain water appears to be quite difficult, and mixing into a protein shake makes a bit difficult to take down (better then water.)

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 Posted 12/19/2011 5:11:41 AM
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People use water or juice.  You can use a blender if you have a hard time mixing it.  You can also put it on your tongue and wash it down with a liquid.
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 Posted 12/22/2011 6:45:37 AM
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To Pamoja, your questions have been forwarded to Life Extension's Product Development Department who is formulating a reply.  Due to my upcoming vacation, it may be posted after Christmas.

Keep in mind that Life Extension has been formulated to allow the inclusion of the most nutrients possible in the smallest amount of tablets, capsules or powder to be taken daily, and to best meet the needs of the majority of those who wish to take a multinutrient supplement.  Many people purchase each nutrient in their program separately and take them at the optimal times, which may, in some cases, be separate from other nutrients.  For fat soluble nutrients in a liquid-filled softgel capsule, you may want to look into Life Extension Super Booster http://www.lef.org/Vitamins-Supplements/Item01590/Super-Booster-Softgels-with-Advanced-K2-Complex.html
Post #4578
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 Posted 12/22/2011 1:18:53 PM
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DDye (12/22/2011)
To Pamoja, your questions have been forwarded to Life Extension's Product Development Department who is formulating a reply.  Due to my upcoming vacation, it may be posted after Christmas.

...For fat soluble nutrients in a liquid-filled softgel capsule, you may want to look into Life Extension Super Booster http://www.lef.org/Vitamins-Supplements/Item01590/Super-Booster-Softgels-with-Advanced-K2-Complex.html


Thanks a lot Dye, great idea to have my questions and suggestions forwarded. And no need to hurry (actually I would really regret having posted my wish-list AFTER ordering a years supply, if some of its items would be implemented instantly now.. Crying ):

And as I already acknowledged, a fat-soluble multi which would suit the majority would really be a genius act. SuperBooster is only a very tiny step in that direction. What would exclude it for the majority (and me) are the 200mcg of Selenium, which together with the 200mcg of Selenium from LEF mix I personally wouldn't recommend to take daily without regularly monitoring selenium tissue levels, or some acute diseases, where there isn't the time for monitoring first. But if only taken every second day (which would cover my need of selenium for normal tissue levels) I still would want to get each of its other ingredients additionally separate again..

It would also be really difficult to serve a majority with the essential vitamin D3, where I personally need about 10.000 IU in oil at the moment (double in dry capsules) to reach my desired serum level. Still, given that 25(OH)D3 serum levels would be monitored, about 5.000 IU would probably constitute the cut-off where a most would benefit.

It would really have be wisely evaluated which nutrients at what amounts are essential for disease prevention and therefore serve most customers with this aim - and avoid all unnecessary duplicities with LEF Mix.

For example: one of it's 2 distinct softgels could contain vitamin K1, A, tocopherols (other than alpha-), lycopene.. and a second containing tocotrienols, vitamin D3, K2s, astaxanthin..
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 Posted 12/22/2011 1:35:59 PM
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Selenium is not included in the next version of Super Booster.
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