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How to reverse grey hair

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 Posted 12/30/2013 9:13:41 AM
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Pseudocatalase - I appreciate you answering everyone's questions on here.  It's added to your credibility and I'm definitely going to order some of your cream.  I don't know if it'll work for me or not, but it's probably as good as anything I can try right now.

Here's my question - is there any alternative to the narrowband UVB lamp?  I'm wondering if a SAD lamp would work since it is supposed to mimic the effects of sunlight.  With the SAD lamp, if there is any effectiveness, it would have to be something like 20 minutes per day (every day) and not the 3-ish minutes for 3 days per week of a UVB wand.  Your thoughts?
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 Posted 12/31/2013 1:49:05 AM
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@stefanovic, 3-4 months is a tricky target. For someone with mild vitiligo, that would be one order of lotion. For someone with bad vitiligo, it could be 10+.  For someone using shampoo, it would be 1 or 2 bottles (depending on use and amount of hair).  All ingredients in pseudocatalase are below the regulated levels for the US and any EU country, so there is no problem carrying it with you. 
  
@gotsomegrey, the concept behind the UVB narrowband lamp is that it causes cellular responses that activate the MC1 receptors. The MC1 receptor is the MelanoCortin 1 receptor that is one way to tell the skin to amplify pigmentation processes. SAD lamps work, instead, to present blue light to your retina to reset your Circadian rhythm. They are really useful and cool for that purpose, but they have no role in pigmentation. An easy alternate, depending on availability, is regular sunlight exposure.  
  
The narrowband UVB lamp, however, targets the MC1 receptor response while presenting 20-100 times less overall UV to your skin as you would need to get to receive the same MC1 receptor response from sunlight. For this reason doctors feel safe in prescribing them to patients with vitiligo, and they truly work. Your skin is safer using the narrowband UVB lamp than using the sun.

There are a number of people working on MC1 topical pharmaceuticals, but none are really available yet. There are some bodybuilders using it off-label as an injectable (causes an overall body natural tan). We believe that this type of pharmaceutical will be a huge future direction in treatment of gray hair and vitiligo, but it is not as mature a technology as pseudocatalase yet. 
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 Posted 12/31/2013 6:04:39 AM
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Thanks for your quick replies, Pseudocatalase. I suppose your nickname on ebay is pseudocatalase. If I order, will I get the powder and mixing stuff with instructions at home. I remember a couple of weeks ago ebay gave me the notification that I might not be able to order from Belgium but now it seems to be removed.
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 Posted 1/1/2014 1:24:11 PM
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Hi @stefanovic, I am the "seller" pseudocatalase on eBay. 
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 Posted 1/1/2014 2:42:56 PM
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Thank you, Pseudocatalase. My question is: if I place an order, do I get the mixing stuff and powder or the mixed lotion? I'd like to go for the first option.
Is it safe to use on eyebrows and eyelashes without feeling irritation?

I've also wondered what it would do to lighter non greying hairs? Would they get darker as well ( my lashes are much lighter than my head hair, that's why)
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 Posted 1/1/2014 6:41:00 PM
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I think I can answer that question for Pseudocatalase since I just ordered his product from Ebay.  There is a drop-down box on the ebay listing where you select whether you want to order the powder, lotion, or shampoo.  The price is cheaper for the powder of course.
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 Posted 1/2/2014 1:37:33 AM
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@stefanovic, I outline in a post above why we recommend people get the pre-mixed variants. The basic reason is that pseudocatalase doesn't last long unless mixed with a suitable carrier and stored in an airtight container. We went to a lot of trouble to find suitable carriers for people in the USA (European users of the lotion can try to find Neribas cream). 
  
Pseudocatalase has been used for about 15 years with minimal side effects. In fact, the whole "pseudocatalase on hair" idea was started when a published study showed that a whitened vitiligo eyebrow had repigmented after treatment. That's not proof it will work for you, but it is proof that it can work for some people. But back to the point, we don't anticipate any irritation at all. 
  
Pseudocatalase will increase pigment in hairs if you respond. Most people have two basic hair pigments, a eumelanin (dark) and a pheomelanin (light). In one of us, they are brown and blond (could be red and black, brown and black, etc). If pseudocatalase increases one, it will also increase the other. A side effect is that some people see lighter pigment in their hair that has been absent for some time. The types of pigment present, and darkness of hair in general, will stay in the range that you are born with. If you have brown and blond pigments, you probably lost the blond first and became brown/gray/white. Well, if you re-pigment you will see blond again as well as more brown. Brown/blond/gray/white. 
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 Posted 1/2/2014 2:04:58 AM
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I live in Belgium and I only get 1 option: pseudocatalase powder 10,75 grams.
In my country they sell Neribas cream containing: Aqua, Petrolatum (Vaseline), Paraffinum liquidum, Stearyl alcohol, PEG 40 stearate, Polyacrylic acid, Disodium EDTA, Sodium hydroxide, Methylparaben, Propylparaben.

Is this the right one?

As it is a cream I wonder how you mix it with pseudocatalase to get an active product?


I've experimented with melanotan in the past and it darkened the non greying hair growth although my eyelashes remained lighter. I wonder what the combo melanotan and pseudocatalase would do to eyelashes? 1- you increase your eumelanin and 2-you add pigment with the catalase.
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 Posted 1/2/2014 2:16:04 AM
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@stefanovic, the powder comes with instructions for how much carrier to mix it with. That is the correct Neribas. 

Please keep in mind that pseudocatalase does not pigment anything directly. It only gets rid of H2O2 in the skin. This removes a hazard for the pigment producing cells so that they can begin to pigment again. It is almost always the case that repigmentation is a slow process, and you should expect GOOD results on the time course of 12-18 months, and not on the time course of a few weeks. With a pseudocatalase product, people see just noticeable results in 3-4 months. And any pigment that gets produced is coded in your own DNA - pseudocatalase will not change your pigments. 

Melanotan is not an approved product, and you are taking your safety into your own hands when you use it. I think combining an MC1 receptor agonist (like melanotan) with a pseudocatalase product is the most effective thing you could do to repigment. In vitiligo, for example, people combine narrowband UVB with pseudocatalase to get full repigmentation on that 1-2 year time course. 
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 Posted 1/2/2014 3:04:33 AM
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Thanks a lot, Pseudocatalase.

Off topic: I've known a couple of people having used melanotan on a constant basis for almost 10 years, having had regular bloodchecks and everything was fine. The few horror stories online have generally nothing to do with the use of melanotan itself. Don't want to promote anything but it's just something I've noticed and I'm of course no specialist.


You say: the powder comes with instructions. So, do I have to buy anything to mix it with except for the Neribas?
Does pseudocatalase protect against further greying too?
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