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How to reverse grey hair

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 Posted 11/24/2013 1:03:47 PM
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Hey @wisdom1st,

Have you got any update to report. I think you are in week8 now.
Also, I want to ask you. Did you see any positive or negative effect on hair thinning. I know this has not been studied yet but I cannot help thinking that clearing the scalp from oxidative material should create healthier environment for hair growth.

Looking forward to hear you updates.
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 Posted 11/25/2013 5:06:43 AM
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@Romi

I am in my 40's, and I have a full head of hair. Grateful for that. I don't know if you could correlate graying and thinning because we've learned that H2O2 is what bleaches the hair making it gray/white. As far as thinning is concerned, it appears this oxidation has no effect on some because there are plenty of people with a full head of gray/white hair.

I have nothing new to report with regards to pigmentation acquisition.  Again, unlike Jcoireangus, I did not see notable changes while using Depo. But we've learned that some bottles did not pass the H2O2 test, and some did. Jcoireangus must have had the latter. I may have too, but I did not notice positive results. I went right into pseudocatalase when I was finished with the Depo. I have scattered hairs that have re-pigmented; a very, very small fraction of 1%.  But the fact that there are a few, leads me to hope for many, many more. And only time can answer that. I will continue using the product, and I will certainly post on this forum when I see escalated results. 
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 Posted 11/26/2013 6:50:09 AM
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Depo Melanin does not work, nobody buy it!!
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 Posted 11/27/2013 6:44:04 PM
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Guys,

Depo has very fast and very strong reaction, i made a video in the following link, as u can see, it is really reactive to h2o2, and with this strong reaction, my bet it should be effective immediately, but unfortunately i am using on my beard since a month, and nothing positive, and i do not believe if i continue to use this 2 more months, something will happen, so, this leaves us with 3 options,



https://www.dropbox.com/l/DJ40Gm66FnzvPtJyB6DESd

after 1 minutes taken photo,

https://www.dropbox.com/l/9Tm8biBttg9XksAjW3Zjdf

1- either theory is not true, but scientists proved this right??? with age decreasing catalese, and h2o2 washes the hairs to white???

2- or depo can not penetrate to skin, because such strong reaction if could penetrate to skin, i guess in a few days we should see, beard turning to black.

3- or depo can penetrate the skin, but hair coloring pigments are dead already, and can not be revitalized, what does scientists say about this??? if we get rid of excess h2o2, can hair pigments be built again??? 

Whatever my dmso is arriving monday, like edison did when inventing the bulb, i will try anything and everything and will find a solution hopefully.

have you ever heard of catalase in an injectable form??? maybe injection would be better???
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 Posted 11/28/2013 4:59:37 PM
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Be careful with DMSO.  As mentioned elsewhere, it acts as a carrier for whatever it is applied with.  Who knows how these chemicals will act in your body if rapidly absorbed through the skin?  Durk Pearson always recommended that the area be scrupulously cleaned first and bandaged afterward so that no impurities would be carried into the body. 

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 Posted 11/29/2013 6:09:32 AM
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Hi @TruthandBeauty,

the best scientific knowledge on pigmentation of hair says that hair follicles that lack pigment can be repigmented. This process is very very slow (more than a year in treated vitiligo patients) and is sensitive to activation of the melanocortan 1 (MC1) receptor. This receptor is typically activated by UV light on the skin.  There are peptides that bind this receptor - and injection of them under the skin will lead to an entire body tan (and presumably a speeding up of hair follicle pigmentation). The safe, accepted, way to speed up repigmentation is UV light exposure. Use of the peptides is mostly unexplored with respect to safety, and they only work via injection at a systemic level - not topically where needed.

Hair follicles lose pigment in multiple ways. The general level of inflammation goes up with age, and this causes an increased immune "tone" which leads to higher H2O2 levels. The cells that produce pigment are very sensitive to H2O2 levels, and can die from this exposure. Elevated cortisol levels (which also occur with normal aging) will cause the melanocyte stem cells to differentiate into melanocytes. The stem cell population can become depleted, which eventually leads to loss of pigment cells. The pseudocatalase products work only on the H2O2 levels. So those ways of losing melanocytes are balanced against the replenishment by UV light.

If you are really gung-ho about this process, you probably want to figure out how to use a UV light wand in conjuction with a pseudocatalase product. The science says this approach will have the greatest chance of success.  But even with a UV wand, a LOT of patience is required. The pigments return on the order of months and years, not days and weeks. 

MOST people using our pseudocatalase product see noticeable return of pigment within 3-4 months, and very slow progressive return of pigment thereafter. It varies from person to person. I wouldn't say it looks like it is going to turn white hair entirely brown, but going from all white to salt-and-pepper gray is entirely possible, or from salt-and-pepper gray to slightly darker salt-and-pepper. But best responses require a LOT of patience.  
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 Posted 11/29/2013 11:01:55 AM
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Pseudocatalase, can you recommend a light wand? I generally avoid direct sun exposure and when I am in the sun I wear a hat. I thought your shampoo could work without UV exposure?

What are your thoughts re the pics posted above showing the reaction of Depomelanin with Hydrogen Peroxide?
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 Posted 11/29/2013 12:54:34 PM
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Sorry if this has been thoroughly discussed here before, but olive fruit/leaf extract for diminishing H2O2 (taken internally). . . would a high dose of this have an effect for purposes of diminishing grey hair?  It works for the heart and pancreas, why not the hair follicle?


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 Posted 11/29/2013 1:21:42 PM
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@wisdom1st
Just for clarification: You're saying only 1% of your hair is currently gray?

Have you noticed any change of pigment in the hair that isn't gray?

@Pseudocatalase
Have you ever read the L'oreal gray hair patent? http://www.google.com/patents/US8445004

Keep in mind it was filed before the H202 discovery. However, there are some interesting tidbits within. I would like to know if you gather anything from it using the knowledge/experience you have on the subject?

@Truth and Beuty
"3- or depo can penetrate the skin, but hair coloring pigments are dead already, and can not be revitalized, what does scientists say about this??? if we get rid of excess h2o2, can hair pigments be built again??? "

This is the most interesting question of all. Is removing H202 from the hair follicle enough to get fully pigmented hair? What if someone used pseudocatalase for 1, 2, 3, 4, or even 5 years? Would the hair regain full pigment regardless of age? Will it take some sort of cosmetic treatment outside of H202 removal? Pharmaceutical drugs? What if someone used pseudocatalase BEFORE they turned gray? Would it stop the graying process from ever occurring or at least slow it down? These are things we don't know (although maybe someone somewhere working on the problem does).

I'll be ordering Pseudocatalase's product shortly (I was travelling) and will report on it. I'm very healthy, far from middle age, and have less than 1% "bleached hair", so I have some advantages. From what I've read and gathered on the subject I predict it will greatly slow the process down or stop it all together.
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 Posted 11/29/2013 5:33:29 PM
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@Truth and Beauty - Depo claims to have catalase and pseudocatalase.  Natural catalase will not penetrate skin, but it should bubble up when put to  the peroxide test. Bottom line, the results of a peroxide test for depo melanin cannot determine if there is pseudo catalase in the product.
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