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How to reverse grey hair

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 Posted 6/6/2014 6:23:41 PM
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I don't know, onion juice seems in the same category as Amla oil, PABA, and the "potions" that probably don't work.
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 Posted 6/9/2014 9:44:42 AM
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@cyclonjimz: On fact 7:  There is a very logical possible explanation as to why PC has not been mass produced by some big company.   
  
There is more than one reason. The primary reason is the response is slow. The secondary reason is the shelf life. NOTHING gets mass produced with a shelf life under 6 mos. For example, Vitamin C is a potent collagen booster in skin. Its modified forms are significantly less helpful. The shelf life of Vitamin C is roughly 2 months, maybe twice that if kept refrigerated and out of light. There are very few pure Vitamin C  (L-ascorbic acid) products out there, and none mass produced (Paula's Choice a notable exception), and people constantly have problems with deactivation. Pseudocatalase has a longer shelf life than Vitamin C, at least double, but the problems still exists. Hard to have a producer -> wholesale -> retail chain. 
  
As with any limitations to our product, we concern ourselves greatly with trying to improve the product and its delivery to our customers, and we are constantly working on new products to overcome those limitations (we hope to have some useful variants in the not too distant future). 

With respect to UV damaging skin - of course it is damaging. Any amount of UV is damaging. It also has beneficial effects through Vitamin D and alpha-MSH production. In younger people, larger amounts of UV are tolerated because the skin repair works faster. In older people, the repair process slows, and UV causes skin to become damaged. Narrowband UV allows the beneficial effects with a more than 10-fold reduction in the damaging effects.   
  
If you use pseudocatalase and want to see if there are effects, we HIGHLY recommend taking pictures of hair under the exact same lighting conditions with the hair cut to exactly the same length. Then, you can make some sort of judgments. Most people, under such conditions, can seem some change in 3-4 months. Few are as robust as Don't-Call-Me-Santa. However, combining pseudocatalase and narrowband UV will generate a response similar to santa in most white haired individuals who were dark haired in youth. 
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 Posted 6/9/2014 11:47:19 AM
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I really hope there will be improved versions of the product in the near future as the success rate of users on this forum is very low. I have taken pics in october last yr and last week and it was about the same, probably a bit more greying. I needed a cut because shampooing twice a day had destroyed my hair.

I've been in touch with quite a few long term LLLT users and the product maker assured me grey hair has been reversed when using this device because of an increase in SOD. If you'd google grey hair and LLLT you get a lot of hits. It must do something.

My next step is the melitane. Already got it at home, now I'm still waiting for the carrier DMI ( is currently being processed by customs in my country). Hopefully I'll have it this week.
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 Posted 6/9/2014 2:29:34 PM
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@Pseudocatalse: Glad to see you're
Working on new products as I would pay a good amount of money for something that works.

I just wonder why the response have been so poor in the people on this board that have tried it. 

What adjustments exactly do you think could
Be made in order for the product to be more effective?
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 Posted 6/9/2014 2:55:57 PM
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@Pseudocatalase , 

you are wrong on Fact 7 as well as many other facts you stated on this forum. Shelf life time is not the reason PC isnot out to production lines from Schallreuter lab. According to her website,the shelf life time of PC_KUS is two years and here is the link:

http://www.vitiligo.eu.com/behandlung_en.php

@Ladd,

I don’t think the excuse you are suggesting for Dr Schallreuter is  valid. Saying (qoute: "Maybe she is happy consulting and researching") is ridiculous. Thereare 10s-100s of millions of vitiligo sufferers around the world. How can a scientist/inventor possesses a key to relieving them just choose to treat the elite at her clinic. If its money she wants, she could make a lot more by selling online and shipping to other places or licensing to pharmaceutical companies. If fame whatshe is after, that will do it too.

I believe the execuse Dr Schallreuter has given over theyears was that: the treatment is tailored specifically to every patient need and this is why you need to visit her clinic ......... That is ridiculous too.Dermatologists around the world aren’t retarded, just give them a manual, everyone can read nowadays.

As a vitiligo survivor myself, I cannot help it but feel disgusted about that. I hope medical authorities would audit her one day.



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 Posted 6/10/2014 3:20:58 AM
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@romi, the shelf life of the mixed pseudocatalase is indeed quite long, if stored suitably. However, once you add it to a cream or shampoo the shelf life becomes quite short. There are also many problems with allowing customers to mix and store their own cream or shampoo that will decrease efficacy.

Schallreuter has published, in peer review journals, very high response rates of vitiligo patients to pseudocatalase cream treatment and a quite modest application of narrowband UV. One of our team is using such a treatment and is definitely responding well within the ranges Schallreuter published. Her work has been directly compared to the outcome if you simply use a lot of narrowband UV treatment instead, and the benefits of the pseudocatalase are modest when you already have a robust narrowband UV application (note: this is all published and reasonably well known). The data all fit a model in which the pseudocatalase blocks the destruction of melanocytes, which is a rapid process, and the narrowband UV expedites the melanocyte replenishment process, which is very very slow. 

I honestly have no specific insights into what motivates Schallreuter. Many scientists are happier doing science than providing customer service...she has helped thousands of vitiligo patients, but the commercial uptake slowed considerably after that one study that compared heavy UV narrowband with and without pseudocatalase in vitiligo patients. 

@stefanovic, we will look into LLLT, thanks.

@EN8686, I don't discuss such things in such forums for fairly obvious reasons, but I will try to go faster.
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 Posted 6/10/2014 7:45:26 AM
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Also, as an addendum, why has the response of those on this board been so poor?
  
Without seeing controlled photographs taken under the same lighting condition, with the same hair length, it is difficult to assess response. Our initial, and continued claim, is that most (but not all) people will notice some modest change in 3-4 months. Those who do not should not continue to purchase and try our product. However, to determine if there is a response may require a controlled scenario that few are following. 
  
Our best local responder, don't-call-me-santa, was white haired and white bearded when he began, and is now mixed gray/black/white haired with mostly white and some black hairs in the beard. It is a remarkable change, in a year, but it is not as though he changed that much in 3-4 months - much less like he grew dark hairs out by the roots.  
 
It is important we stay honest about expectations with people that use our products, because we know we can help some people, even if the product is not the miracle that some people hope it to be. But with continued use many people will turn the grey hair clock backwards in time. Of course they will probably grey anyway, but if you could push greying back 5 years, or 10 years, or 15 years, would you?   
  
One of us (not don't call me santa) is a more modest responder, with the grey hair clock pushed back 3-4 years. Use for us is continuing. And, of course, we hope to have new, better, products in the future that can accelerate the backwards greyhair clock that we hope for. 
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 Posted 6/10/2014 8:21:00 AM
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@Pseudocatalase,

why do you insist on making up you own carrier over using the well tested Neribas as a carrier. It is being sold over eBay and I am sure you can secure a bigger shippment from Europe.

When I mixed up my own cream using Neribas and your pseudocatalase powder, the cream interacted much quicker with H2O2 than your cream. I also felt it got much better absorbed into the skin.  I already gave you this feedback a while ago, but you seem stuck in your ways. 
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 Posted 6/10/2014 8:23:10 AM
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@Pseudocatalase: Could you expand a little bit on what younger people could expect? I've got maybe 100-150 grey hairs, obviously still mostly black. This began at the age of 26, about a month shy of turning 27. I will b2 28 in August, so it has been about a year. Obviously this is premature and not age-related greying.

Since you talked about that looking at individual hairs is not a good way to judge results, how would someone like me judge whether its working? The picture route probably won't work, since I have to take the picture at a certain angle to even notice the grey hair.

I had thought that a good indicator would have been that the grey hair halted. That has not been the case, however, as there have been more grey hairs than when I started using the product.

I'm sure the stress has contributed, as I've been under a tremendous amount of emotional stress the last year or so. My parents also started getting grey hairs in their 20's so that's part of it. I guess the question is-- does stress cause a buildup of oxygen peroxide, causing the greys to come in, or does the stress trigger a different mechanism that causes the grey? If it is the later, then I would assume pseudocatalase would not help. But stress is so subjective and everyone experiences it, making it hard to really quantify.  
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 Posted 6/10/2014 8:58:10 AM
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I think most of us have taken before and after photographs. I've even had blood checks on a regular basis. All it did, was breaking down my hair. Shampooing twice a day for 5 minutes is never a good idea.
When you buy some hair dye ( for instance) and you let it sit for half an hour, everyone will respond. The end results might vary but we will respond. Same for UV exposure, cleansing our skin with soap. We all response, some in a different way but there is some response.
The thing is: 5-10 users on the forum have no response. Even though it's possible some have a different background, it shows that IMHO very little is known about the pseudocatalase route when it comes to reversing grey hair. There is a theory and it's a shame Mrs. Schallreuter doesn't want to give more info ( that's what I think at least). But is this story really like: no response after 3-4 months, then quit because you will never respond? Or has it something to do with the fact that this treatment needs a few more adjustments before it's effective.
The LLLT builder told me his device works also by increasing SOD, it would be cool to know how that exactly works ( you find some real people testifying they used it for baldness but the hair darkening happened to be a side effect)
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