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LE Arthromax VS other Brands of Joint Supplements

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 Posted 8/29/2014 2:28:29 AM
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Life Extension Arthromax has 10mg of Collagen
Life Extension Fast Acting Joint Formula has 40 mg of a proprietary blend including Collagen
Doctor's Best Hyaluronic acid Capsules has 600mg Collagen

Clearly Doctor's Best is way ahead of any Life Extension Joint Supplements or am I reading this wrong?

This is my first post here so unaware of the rules but I am in a hurry to try this Collagen UC II instead of the Glucosamine+Chondroitin that I have been using for a long time. Please help me make sense of all this.


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 Posted 8/29/2014 4:50:55 AM
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The undenatured type II collagen content per one serving (two capsules) of ArthroMax(R) Advanced with UC-II and AprèsFlex®  http://www.lef.org/Vitamins-Supplements/Item01618/Arthromax-Advanced-with-UC-II-ApresFlex.html is 10 mg.

The product contains:

Glucosamine sulfate 2KCI (derived from corn)

1500 mg

AprèsFlex® Indian frankincense (Boswellia serrata) extract (gum resin) [std. to 20% AKBA† (20 mg)]

100 mg

UC-II® standardized chicken cartilage (providing 10 mg undenatured type II collagen)

40 mg

Boron (calcium fructoborate as patented FruiteX B® OsteoBoron®)

Fast-Acting Joint Formula contains 40 mg Hyal-Joint®, which consists of hyaluronic Acid (sodium hyaluronate), collagen, and glycosaminoglycan complex http://www.lef.org/Vitamins-Supplements/Item00965/Fast-Acting-Joint-Formula.html

Hyal-Joint® [Hyaluronic Acid (sodium hyaluronate), collagen, and glycosaminoglycan complex]

40 mg

Decursinol-50® (Angelica gigas Nakai) extract (root) [std. to 0.1% decursinol (0.2 mg)]

200 mg

Solubilized Keratin

300 mg

Doctor's Best Hyaluronic Acid with Chondrotin Sulfate contains (in two capsules):

BioCell Collagen II®, providing: 1000 mg                 
Hyaluronic Acid 100 mg                  
Chondroitin Sulfate 200 mg                  
Hydrolyzed Collagen Type II 600 mg

While it's not possible to vouch for the quality of their product, if it is only collagen you are looking for, your math is the same as mine. The two Life Extension products you asked about contain collagen as part of formulas that offer varying nutritional approaches to arthritis.


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 Posted 8/29/2014 6:29:56 AM
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Thanks for the prompt response, appreciate it.

I am not after Collagen alone but a joint supplement that offers enough Collagen with some Hyaluronic Acid. The problem is that I don't know how much is "Enough ". Can you shed some light on that? Life extension also offers a stand alone Collagen 2 supplement that has 40mg UC II. Is that enough? The Doctor's Brst supplement with 600 mg UCII would seem like an overkill then.

While we're at it, could you please clarify if any of the ingredients in your Fast Acting Joint Care would aggravate GERD as I live with that. I am not looking at this supplement for pain relief as the Methotrexate I take has that part covered for my Psoriatic arthritis. I am interested in it for my weak knee that has dislocated twice in 15 years and MPFL Reconstruction has been suggested by some while other doctors seem to think exercise and nutrition are enough. I think the Fast Acting Joint Care Capsules should help with tissue regeneration and prevent further damage.
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 Posted 8/29/2014 6:51:31 AM
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This article might be of interest to you http://www.lef.org/magazine/mag2012/jul2012_Hault-Auto-Immune-Attack-Of-Arthritis_01.htm . 

According to the article's reference 9, participants were fed 0.1 milligrams of solubilized type II collagen daily for 1 month and then switched to 0.5 mg for the next two months. "This dose was extrapolated from experiments in the rat adjuvantarthritis model wherefeeding 3 to 30 ug ofcollagen attenduated disease."

While none of the usual suspects that aggravate GERD are in Fast Acting Joint Care, it is not possible to predict whether any might bother you more than the components of the rest of your diet.


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 Posted 8/29/2014 7:52:27 AM
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Thanks. Do all three Life Extension supplements have the same amount of UC II Collagen:
  • Arthromax® Advanced with UC-II® & ApresFlex®

  • Bio-Collagen with Patented UC-II®

  • Fast-Acting Joint Formula




Fast Acting does not clearly mention how much UC II is in there. All three are priced exactly the same in my Country so I am confused which one to pick up.
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 Posted 8/31/2014 9:30:34 PM
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I would like to see LEF create a product containing the following:

- Eggshell Membrane
- Avocado/Soy Unsaponifiables
- Celadrin® [a proprietary blend of esterified fatty acid carbons (EFAC) (myristate, myristoleate, oleate, palmitoleate, palmitate]

Do research and look these up and you'll see the positive results.

-Tom

P.S. AKBA is great to potentially stop further joint damage with 5-LO inhibition but in reality is only masking the problem? The key is to get to the root cause of joint pain. The compounds above are therapeutic.


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 Posted 9/1/2014 4:43:37 PM
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Tom,

Your request has been forwarded to Life Extension's Product Development Department for their consideration.

D Dye
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 Posted 9/1/2014 8:42:22 PM
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DDye Thanks ... Here are some studies ...


Natural Eggshell Membrane


Clin Rheumatol. 2009 Aug;28(8):907-14

"Natural Eggshell Membrane (NEM(R)) is a new novel dietary supplement that contains naturally occurring glycosaminoglycans and proteins essential for maintaining healthy articular cartilage and the surrounding synovium ... Treatment Incorporating NEM(R) clinical study was conducted to evaluate the efficacy and safety of NEM(R) as a treatment for pain and stiffness associated with osteoarthritis of the knee ... Supplementation with NEM(R) produced an absolute rate of response that was statistically significant (up to 26.6%) versus placebo at all time points for both pain and stiffness ..."

Clin Interv Aging. 2009;4:235-40

"Natural Eggshell Membrane (NEM) is a possible new effective and safe therapeutic option for the treatment of pain and inflexibility associated with joint and connective tissue (JCT) disorders. Supplementation with NEM, 500 mg taken once daily, significantly reduced pain, both rapidly (seven days) and continuously (30 days). It also showed clinically meaningful results from a brief responder analysis, demonstrating that significant proportions of treated patients may be helped considerably from NEM supplementation".

Avocado/Soybean Unsaponiflables

Arthritis Rheum. 1998 Jan;41(1):81-91


Symptomatic efficacy of avocado/soybean unsaponifiables in the treatment of osteoarthritis of the knee and hip: A prospective, randomized, double-blind, placebo-controlled, multicenter clinical trial with a six-month treatment period and a two-month followup demonstrating a persistent effect.

"Overall functional disability was significantly reduced in the avocado/soybean unsaponiflables group. Improvement appeared more marked in patients with hip OA. A residual effect was observed at month 8. Tolerance was good to excellent for most patients ... avocado/soybean unsaponiflables treatment showed significant symptomatic efficacy over placebo in the treatment of OA, acting from month 2 and showing a persistent effect after the end of treatment".

J Rheumatol. 2006 Aug;33(8):1668-78

"Avocado/soybean unsaponifiables prevent the osteoarthritic osteoblast-induced inhibition of matrix molecule production, suggesting that this compound may promote OA cartilage repair by acting on subchondral bone osteoblasts. This finding constitutes a new mechanism of action for this compound, known for its beneficial effects on cartilage".

Celadrin®

J Rheumatol. 2002 Aug;29(8):1708-12

"Compared to placebo, [Celadrin] provides an improvement in knee range of motion and overall function in patients with OA of the knee. [Celadrin] may be an alternative to the use of nonsteroidal antiinflammatory drugs for the treatment of OA".


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Seize every opportunity to put your best foot forward.

Anything worth doing is worth doing well.
If you don't stand for something, you will fall for anything
If everything seems under control you're just not going fast enough. - Mario Andretti
You can't expect to do business today, with yesterday's tools, and be in business tomorrow. - Author Unknown
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Post #13706
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 Posted 9/1/2014 10:15:31 PM
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Well I ordered the Fast Acting Joint Formula considering I can use more than just UC-II and that I am not keen on Glucosamine.
Hope it helps at least a little.
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 Posted 9/3/2014 9:13:36 AM
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Glucosomine and boswellia have been fairly effective for me in reversal of some joint deterioration.

Is everyone aware of the new research showing that misfolded proteins accumulate in bones and joints same as brain and may
account for a lot of the muscoskelatal problems associated with aging?
Post #13715
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