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Which offers the best chance of extended life?

Which offers the best chance of extended life?
Which offers the best chance of extended life?

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 Posted 8/1/2014 3:26:29 PM
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No matter what your own practices are, which do you think will result in the greatest extension of life?

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 Posted 8/1/2014 6:37:56 PM
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Calorie Restriction has the most evidence for longevity, but iron reduction seems to be a promising new longevity theory.  

Cancer and Heart Disease are the two most common killers of the elderly and the elevated iron of age had been associated with both these maladies.  Many believe this is why women tend to live around half a decade longer then men across most all countries and cultures.  Women don't start accumulating excess iron until after menopause and this gives them the edge.  

Bill Sardi's "A Unifying Theory of Aging" is a good thesis on the "over-mineralization" theory of aging.  

The Health-E-Iron site http://healtheiron.publishpath.com/ also has a small ocean of studies backing up this theory.  

Get thee to a blood bank!  Or perhaps IP6 / Inositol Hexaphosphate chelation.  

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 Posted 8/2/2014 5:31:52 AM
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The number one factor to ensure living through the next few minutes is adequate breathing. Given how crucial breathing is just in the short-term, I'm sure that how we breathe plays a role in long-term health also (i.e., exercise, breathing rate and metabolic factors).

Next, applying this same logic would be water consumption.  Ensuring survival through just the next few days is going to involve drinking water. And if it's so entirely crucial for life in the short-term, I'm sure adequate hydration also plays a very big role in long-term health.

And so forth, and so on. . .

But the problem is, of course, is that millions of people who died before us did pretty well on "all of the above" yet still died at quite unremarkable ages.  We're going to have to do very well on all the basics of health now known and then be aided by innovative new technology heretofore unknown by our predecessors.

On a lighter note, here is something:

  10 Reasons to Drink Water



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 Posted 8/2/2014 5:50:50 AM
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As we age, our internal bio-chemistry degrades, and so we must supplement with external natural compounds to compensate.  Otherwise, entropy will take its course.
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 Posted 8/2/2014 6:13:19 AM
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Transpower (8/2/2014)
As we age, our internal bio-chemistry degrades, and so we must supplement with external natural compounds to compensate.  Otherwise, entropy will take its course.


Hello Trans, Yes, this entropy seems an unsolvable problem. And yet MANY plants seem to live possibly forever and surely a very long time if their environment does not kill them.
   A simple but valid example or anology is: To take a photo, print, image of some sort and start making repeated copies of it. As you continue this process the copies get worse and worse. Small errors get repeated and new ones added. Some biologists say the same thing happens with cellular division.
   But if you keep using the original copy you will get very close repros of the original. Maybe there is some way of doing this biologically.   ..Oscar
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 Posted 8/2/2014 6:23:49 AM
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Transpower (8/2/2014)
As we age, our internal bio-chemistry degrades, and so we must supplement with external natural compounds to compensate.  Otherwise, entropy will take its course.



Quick follow up question: Why is it even older men can produce [ with a fertile woman ] healthy offspring, children ?
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 Posted 8/3/2014 7:52:14 AM
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Oscar2u, we can use energy to reduce entropy.  This must come from the outside, to compensate for what is degrading on the inside.  I just got back from the supermarket this morning; I'm amazed at how awful most people look.  They are doing nothing to compensate for entropy.  The very long-lived plants must have "figured out" how to take in exactly the right nutrients to repair their cells.  As it stands now, orthomolecular medicine is mostly trial and error.  In the future I'd expect there to be body scans which will tell us exactly what we need.


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 Posted 8/3/2014 10:58:18 AM
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The answer:  None

You see ladies and gentlemen, there really isn't very many long-term, controlled, human studies that confirm any of those factors will significantly extend one's life.

Nutritional supplements -- Some animal experiments show promise. In humans, certain supplements have shown strong anecdotal and epidemiological success in keeping one healthy. Lots of positive, hypothetical science regarding replenishing the body's declining levels of substances. However, no concrete evidence they provide true life extension.  Some supplements can actually be counter productive, like Lipid peroxidation.

Calorie restriction -- This has shown promise in insect and animal studies but not undoubtedly confirmed in humans.

Exercise -- This has been shown to positively modulate factors like heart and lung function, preserve muscle mass and bone strength, etc., which can allow one to more closely fulfill ones destined lifespan sans disease.  However not much in the way of undoubtedly confirmed life extension.  Too much stressfull exercise can be counterproductive.

Meditation and spiritual practices -- This has shown to reduce cortisol levels, and other stress induced diseases, but nothing undoubtedly confirmed in regard to life extension.

In summary, when we view the published scientific literature regarding engaging in such practices, or eliminating disease risk factors, etc., it is often said "... adds a few more quality years ..."

This is hardly what science considers true "life extension"

The argument can be presented that humans live longer now than the did, say 100 years ago, thus we have extended life.  True, but this is due to better understanding of epidemiology. 

With current wisdom, even the healthiest average human still only lives well under 100 years.

If you're one to follow the scientific theory of dogs age of maturity compared to humans, than humans live shorter lives. A dog reaches sexual maturity around year 1, humans by year 15.  Therefore, a dog at 16 years old has lived an equivalent of 120 human years.

Very, very, very few humans have surpassed the 120 year mark.

My point being is that we haven't made noteworthy strides in human practice.  However that's not to say that we can't or won't.  But I think it will be with some other discovery other than the ones listed in the original poll.

-Tom


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 Posted 8/3/2014 8:10:37 PM
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Probably #2 and #3, but I am not going to restrict my caloric intake that much in order to gain a few years. I think the only technologies that will make a significant difference in life extension are Genetic Engineering, along with Stem cell and cloning technologies. However, I think it's the type of thing that a large group of people would have to work on, (i.e. international collaboration) like when they mapped the human genome.

We probably have a better chance of replacing things as they wear out than we do of stopping or significantly slowing the biological process of aging, but who knows what someone may stumble upon. 
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 Posted 8/4/2014 4:25:55 AM
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Genetic engineering is my best bet as well; however, the poll addresses therapies commonly used and available now.

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