Life Extension Forums




A new NAD+ supplement from LEF ? ( hopefully )

Author Message
alc
 Posted 4/15/2014 6:10:48 PM
Spectator

SpectatorSpectatorSpectatorSpectatorSpectatorSpectatorSpectatorSpectatorSpectator

Status: Regular Customer
Group: Forum Members
Last Login: 4/20/2014 5:38:37 PM
Posts: 2, Visits: 13
After I red about the study that prof. Sinclair did and published in December, I googled for NAD+

I found out that Biotivia is developing a product that they claim is doing the same thing, like the study did.

http://www.biotivia.com/

You might read on their web site about  MitoTrans* (NAD+)

http://www.biotivia.com/nad_plus_mitotrans_antiaging.html

I'm interested in reading others comments/thoughts about this product that Biotivia is producing.

Adrian
Post #12610
Add to Twitter Add to Facebook
 Posted 4/16/2014 11:00:36 AM
Enthusiast

EnthusiastEnthusiastEnthusiastEnthusiastEnthusiastEnthusiastEnthusiastEnthusiastEnthusiast

Status: Member
Group: Forum Members
Last Login: 8/29/2014 6:32:44 PM
Posts: 35, Visits: 566
alc (4/15/2014)
After I red about the study that prof. Sinclair did and published in December, I googled for NAD+

I found out that Biotivia is developing a product that they claim is doing the same thing, like the study did.

http://www.biotivia.com/

You might read on their web site about  MitoTrans* (NAD+)

http://www.biotivia.com/nad_plus_mitotrans_antiaging.html

I'm interested in reading others comments/thoughts about this product that Biotivia is producing.
Adrian


Interesting. I have read somewhere that NAD itself is too large of a molecule to be absorbed.  Perhaps their delivery system gets around that.  There isn't any reliable data regarding NAD enhancement in humans with any specific product or dosage of products.   According to Guerante and Sinclair, NR being a small molecule is the best and most direct precursor of NAD
This is another reason that it would be interesting to see how LEF addresses this, and which molecule they will choose to use.  The problem with anything other than plain old niacin, is patent issues. 
Post #12621
Add to Twitter Add to Facebook
 Posted 4/25/2014 3:19:04 AM
Forum Associate

Forum AssociateForum AssociateForum AssociateForum AssociateForum AssociateForum AssociateForum AssociateForum AssociateForum Associate

Status: Member
Group: Contributors
Last Login: Yesterday @ 11:50:22 PM
Posts: 1,621, Visits: 2,280
DDye (4/14/2014)
Albedo,

Product Development provided the following response:

We greatly appreciate the feedback and are continuously scouring emerging research for synergistic and novel ingredients. However, we do not disclose information regarding our plans for future product development. 


OK thank you for the feedback.


Tags:
Post #12726
Add to Twitter Add to Facebook
 Posted 5/13/2014 7:03:20 AM
Forum Associate

Forum AssociateForum AssociateForum AssociateForum AssociateForum AssociateForum AssociateForum AssociateForum AssociateForum Associate

Status: Member
Group: Contributors
Last Login: Yesterday @ 11:50:22 PM
Posts: 1,621, Visits: 2,280
albedo (3/29/2014)
There is a presentation from Guarente. If time I might try and go to understand better. Any question I can ask?
http://sv.epfl.ch/life-science-seminar

Date

May 9 

Time

11:00

Speaker

Leonard Guarente 

From

MIT, Laboratory for the Science of Aging and Koch Institute, Cambridge, USA 

Title

SIRTUINS, NAD and AGING 

Location

SV 1717a 

Host

Johan Auwerx 

Student lunch

Students : sign up for lunch 


Unfortunately the meeting was cancelled as per the following link:
http://memento.epfl.ch/event/sirtuins-nad-and-aging/
However, at the bottom of the link, following the abstract, you have a good link to a recent review work: "Calorie Restriction and Sirtuins Revisited". The paper replies to some of the recent challenges on the reported effect of sirtuins mediating CR hence extending longevity. Note at the very end: "Finally, supplementation with the NAD precursorsNMNor nicotinamide riboside has been shown to counteract aging (Ramsey et al. 2008; Mouchiroud et al. 2013) and may offer another strategy of keying sirtuin surveillance to forestall aging and diseases."


Tags:
Post #12816
Add to Twitter Add to Facebook
 Posted 5/18/2014 9:25:50 PM
Spectator

SpectatorSpectatorSpectatorSpectatorSpectatorSpectatorSpectatorSpectatorSpectator

Status: Regular Customer
Group: Forum Members
Last Login: 5/19/2014 6:35:16 AM
Posts: 3, Visits: 6
Niagen is NR cholride and not NR. I suspec the chloride form has bioactive differences than NR. NR is very expensive. NR chloride is much less expensive.
Post #12896
Add to Twitter Add to Facebook
 Posted 7/9/2014 5:40:21 AM
Fan

FanFanFanFanFanFanFanFanFan

Status: Wholesale Customer
Group: Forum Members
Last Login: 8/29/2014 8:01:26 AM
Posts: 138, Visits: 1,584
In light of this information on the importance of NAD, would anyone advise if one should continue taking an NADH supplement? It sounds like this pseudohypoxia cell-aging occurs with imbalanced NADH at the mitochondrial cell level, so is taking a dietary supplement of NADH therefore somewhat counterproductive to the goals of life extension?


___________________________________________________________________________________________________


Tags:
Post #13298
Add to Twitter Add to Facebook


Similar Topics

Expand / Collapse

Reading This Topic

Expand / Collapse