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Testosterone Replacement Therapy For Men: my experience

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 Posted 8/25/2014 9:07:48 AM
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kaypeeoh (8/25/2014)
Bad Robot (8/25/2014)
kaypeeoh

Nice post, but you didn't say whether you've had any PSA tests and what they were in relation to your supplement and diet changes. The PSA tests over time is a pretty good indicator of what's happening to your prostrate and if you have that info please post it.





When I was diagnosed with BPH several years ago the PSA was 0.2.  Over the years it's gone up to 0.3 then 0.35 but I haven't had it tested in the past two years. 

BTW, it's the prostatic vein, not the artery, that's involved in causing BPH.  I just noticed my mistake.

kpo


This concept about the prostatic vein. I'm having trouble picturing it, would you by chance have a picture that would illustrate it, and give us an idea of how extensive any surgery might be. On the surface it sounds like an easier surgery than removing the prostrate itself. Next regardless of how well it might help, if insurance companies won't pay for it, it's not going to be very popular.
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 Posted 8/25/2014 12:34:07 PM
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Google Gat Gorem and they might have a better explanation.  The vein comes off the prostate then travels up parallel with the spine.   Somewhere around the kidney it inserts on the vena cava.   There are small one-way valves in the vein that keep material moving forward.  These valves become incompetent with age.   Gorem shows there is a connecting vein from the testes.  Then shows the concentration of testosterone is very high in the prostatic vein, the closer it is to the prostate.   By plugging the major vein smaller side veins take over the job of draining the prostate.

kpo
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 Posted 8/25/2014 11:18:41 PM
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Bad Robot, the link I posted gives nice pictures.
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 Posted 10/25/2014 9:19:11 AM
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I never have any luck with the skin surface applications of testosterone enhancements.  Last February I started injections 200mg every 2 weeks.  Brought T-level into mid 300's and all was fine.  Past 6 weeks I started burning up,(day and night) and just found out blood estrogen (E2) is very high.  Not sure what to do now, doctor appoint this next week.  But this is terrible...

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 Posted 10/27/2014 6:18:22 AM
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Aromatase is a natural enzyme  that converts testosterone into estrogen.   Lots of guys who take high doses of testosterone ultimately develop gynecomastia--enlarged breasts--and need surgery to reduce breast gland tissue.  Surgeons do a sort of liposuction to remove the tissue.   Another option is aromatase inhibitors.   Estrogen is also a factor in prostate enlargement.  I take DIM to lessen the conversion of testosterone to estrogen.   5 alpha reductase inhibitors like Proscar stop the conversion of testosterone into DHT.  DHT is a much stronger type of testosterone.  This stronger type is what leads to enlarged prostates.  I'm guessing  could lead to increased estrogen production. 

kpo
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 Posted 5/17/2015 9:16:50 PM
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200mg every two weeks?  That's too infrequently... you might avoid side effects by injecting more often.  

If you inject less testosterone each time, but inject more frequently, your estrogen conversion will go down.  50mg twice a week will smooth out your testosterone levels and cut down on aromatization.   
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 Posted 6/16/2015 6:30:12 PM
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I have always wondered why at age 42 I was very low in T. Only between 208 to 240 of total T. Free direct was always around 9 to 12 while estradiol was well over 40!

I had battled bouts of sexual dysfunction off and on since my late 20's.

When I was only 3 or 4 years old, I had mumps. they "fell" to my pancreas and most likely to my testes. All I remember was being very ill.

I was always very skinny in my life.

I believe that the mumps effected either my testes and or my pituitary gland via mumps orchitis. I remember both an endo doctor and my TRT doctor had questions about my pituitary gland and I even had an MRI of it. Which was normal but there were other signs of dysfunction.

After all these years I may have found the source of my hypogonadism!

BTW, when my iron levels get too high, I take 100mg of lactoferrin because I hate needles.
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 Posted 6/19/2015 12:17:25 PM
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Time for an update, 4.5 years later

Just wanted to share an update since I started this thread and kind of disappeared ...

To quickly recap, I originally tried the highly promoted bio-identical method using compounded cream and in my case it was an expensive flop.  I'm sure it works for some.

I next converted over to Androgel and had better results until starting about two years ago.  I was on the 5mg dose and during an annual checkup, my total testosterone measured well under 300.  My primary Dr. had no idea why, so he simply doubled up my dose to 10mg and that seemed to help, but it was never wow, this is great.

After a couple years, my insurance started giving me a hard time.  They seemed to grow tired of paying for Androgel and they would do things like "forget to authorize" when I show up to pick up and just became a big pain until one day I went to pick up I notice it was changed to some generic gel and I have been on that for about 9 months now.

It seems this gel isn't working as good, but I read somewhere that gel users can reach a point where the absorption just isn't as good as the beginning.  Anyway on my last checkup, my total testosterone was 400 and my Dr was happy with that, but I'm not.  I'm not really feeling any beneficial effects of TRT other than maintaining a lean frame and my Dr. says everything is fine.  It's not fine, so here I go again looking for a new solution.

I gave a quick revisit to the bioidentical method, thinking maybe there have been some advances, but no it looks to be pretty much the same that I encountered before:  washed up Drs without any specialty with endocrinology and lots of Drs who are getting fresh starts after malpractice judgements (seriously, check with your state's MD license board when looking at these Drs and chances are high you'll see what I mean).  In my opinion, based on what I have seen, Bioidentical TRT is for the rich and famous, not the average Joes. 

I'm seriously considering the injection method of testosterone cypionate.  It seems to have a long half life, so the concerns of having huge peaks and valleys doesn't seem so valid.

It's a pain trying to find a good Dr in my area, San Diego CA, who is willing to treat low testosterone to bring it up to optimal youthful levels.  I hope to share a new update soon.
Post #16062
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 Posted 6/19/2015 12:22:39 PM
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Welcome back, seaexplorer.

Have you seen any Forever Health doctors?

D Dye
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 Posted 6/19/2015 12:56:32 PM
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DDye (6/19/2015)
Welcome back, seaexplorer.

Have you seen any Forever Health doctors?



Thank you.  I'm glad this forum still exists.  I'm not familiar with Forever Health but will definitely check them out.  Thank you for mentioning them. 
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