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HepatoPro (Polyunsaturated Phosphatidylcholine) from LEF

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 Posted 9/8/2013 10:02:20 AM
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Ref. HepatoPro (Polyunsaturated Phosphatidylcholine), 900 mg, 60 softgels, Product # 01393

I have noticed, very consistently in many orders, that after only few days after you open the bottle the softgels cover themselves by a thin film of some sort of moisture you can clearly feel on your fingers. No particular smell or taste.

Have you had a similar experience? Is that normal or is there a suspicion of degradation of the product? I store in a relatively cool and dry place and wonder if I should use the freeze instead.

I already asked LEF and wait for reply.

Thank you in advance!


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 Posted 9/9/2013 5:40:29 PM
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Hi albedo; I've had the same thing with both HepatoPro and PhosChol (similar product).  

I don't believe it compromises the product, but then I really don't know.  Looking forward to what you find out from ask LEF.  

I've got a bunch of little film canister type containers and when I crack a new bottle of PPC I split the contents up into about half a dozen of the smaller containers and cap them up.  They stay good as new this way.  

My girlfriend takes PPC for her NSAID irritated stomach and she keeps her PPC in her purse, and often doesn't finish off a bottle for quite some time.  Her's get real gooey but still work just fine for her stomach irritation, so this is another indication that the gooey thing that is going on doesn't hurt the potency.  

Let us know what LEF says about this!  
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 Posted 9/9/2013 10:14:08 PM
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synesthesia (9/9/2013)
Hi albedo; I've had the same thing with both HepatoPro and PhosChol (similar product).


Experienced the same thing with PhosChol, where already upon first opening of the bottle the softgels were covered with a slimy gel-like substance, and then to a lesser extent as you both describe with HepatoPro, despite keeping it in a fridge. Contacted the European distributer about it, if that would be the normal case with PPC? - He never heard any other costumer complain about. Thanks for confirming.
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 Posted 9/14/2013 7:28:30 AM
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This is an extract of the reply I have received from LEF:

"...We apologize for any inconvenience the softgels contained in the HepatoPro have caused. We have forwarded your feedback to our Product Development Department for their review. We welcome your input.

While we have had similar feedback from our customers in regards to the softgels contained in the HepatoPro, we would not suggest storing the product in the freezer or refrigerator. We suggest that you store this product in a dark and dry place, at room temperature and not in the refrigerator.

As defined by the US Pharmacopeia, the upper limit of room temperature is 86 degrees Fahrenheit. For optimal potency, products should not be stored for extended periods at temperatures above 86 degrees Fahrenheit. Product shelf life will be reduced if products are stored at extremes of temperature for sustained periods, especially in humid environments.

You may test the temperatures of different locations in your home to determine the coolest locations. A temperature of 86 may not be “cool”, but meets the upper limit of what is acceptable..."
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 Posted 9/14/2013 8:38:31 AM
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It's interesting they say not to store PPC in the refrigerator...  I read the same thing on Mercola's site about a phospholipid preparation he was discussing.  Refrigeration damages phospholipids!  No explanation why.  

We've had some hot weather lately, and if you can't store your PPC in the frige, and temperatures over mid 80's will damage them, does this mean I must leave the air conditioning on while I'm at work to keep my PPC cool?  

Besides breaking my large bottle down into smaller containers as soon as I open it as I mentioned above, I'm also keeping them in a bottom drawer in a cooler room (North side of the house).  My gooey capsule problems are largely solved this way.  
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 Posted 10/16/2013 1:39:46 AM
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Hello,

I had the same problem with both HepatoPro (LEF) and PhosChol (Nutrasal), seems to be the same manufacturer ("made in Germany"). When ordering several bottles of these products 2 or 3 years ago (different batches and expiration dates), the softgels in each and every bottle were covered with an oily film and sticking and clumping together.

I think the problem was and still is that one ore more or all softgels in the bottles were leaking. Could be a manufacturing problem, incorrect storage or transport (too hot, too cold) ...? Anyhow, problem seems to be evident for a long time. Please see the following links where users discussed it already years ago:

http://www.medhelp.org/posts/Hepatitis-C/Cocksparrow-clairvoyant-Beware-PPC-users/show/596608

http://www.medhelp.org/posts/Hepatitis-C/Warning-about-Nutrasals-Phoschol/show/1668777

I don't know if the PPC really would become rancid when exposed to air (Nutrasal also sells a liquid version and there should be air in the bottle, too) and if it would be bad for your health when consuming it then. I did so and had no negative effects so far, but who knows ... Always hoping that the problem will be resolved but following your recent posts it's still not the case. So for myself I'm not going to order HepatoPro or PhosChol in near future which is really a shame because PPC seems to be a very promising supplement and I don't know an alternative manufacturer/distributor.

Bernhard


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 Posted 10/16/2013 4:04:27 AM
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If you have any bottles that contain the leaky capsules, please contact Life Extension's Member Services department customerservice@lifeextension.com for assistance on returning them.

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 Posted 10/16/2013 7:50:54 AM
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No need to give up on an excellent product Bernhard...  

Simply get thee some smaller containers and immediately upon opening a fresh bottle of PPC, transfer the contents to these smaller containers and cap them up tightly.  They WILL stay factory fresh this way...  Good to the last cap!  

Alternately, you could switch to PhosChol Liquid, which is stabilized with Vitamin-E.  

I really don't sweat the film of a one capsule blowout lightly covering the rest of the caps.  Even if you don't wipe the film off the rest of the good capsules before/as you take them, the amount of oil/product that may (or may not!) have become oxidized is so small it would seem to me to be insignificant to health.  My daily Vitamin-E which I also include in my regime (and take at the same time as my PPC) should be more than enough to neutralize the wee bit of oxidized product on the outside of a cap.  I also do not believe there is any evidence that would indicate a bit of oxidized product on the outside of an intact/remaining capsule would somehow contaminate the contents within the intact capsule.  

A certain amount of oxidation will occur in many (all?) types of supplements between the time of manufacture and the day they are consumed, whether one or more capsules are compromised or not.  All supplements and medicines have a "rate of decay" or they would never expire...  This doesn't mean that all supplements and/or medicines are bad and should not be taken!  

Throwing the baby out with the bathwater is not the answer.  With a bit of ingenuity, you can have your PPC and take it too!  Smaller bottles are the answer.  Buy smaller bottles of PPC more frequently, or buy in bulk and break the large bottle down into small containers for storage.  Wipe the film off remaining caps (as you take them) when there is a blowout of a single cap.  The stuff inside the intact caps is still good.   Why wouldn't it be?  
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 Posted 10/17/2013 11:09:37 AM
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DDye (10/16/2013)
If you have any bottles that contain the leaky capsules, please contact Life Extension's Member Services department customerservice@lifeextension.com for assistance on returning them.


Thank you for the info, DDye. As far as I am concerned I have no bottles left with leaking softgels. I have not bought HepatoPro (or PhosChol) for 2 or 3 years.

Hi synesthesia,

the softgels were already leaking when opening the sealed bottles for the first time, so I see no benefit in transfering the capsules into smaller containers. I don't know if the oil had become oxidized, how many capusels were leaking and if this would be bad for your health but even LEF recommended not to use them in this case (according to the user in the first link in my previous post).

Bad or not, honestly said I'm not willing to pay much money for a supplement when it can be expected that every bottle contains one or more leaking capsules. I have used a lot of supplements in softgel form from different manufacturers in the past (Vitamin D, K, Fish Oil ...) but I never ever had a problem with leaking capsules. So I think LEF and Nutrasal should contact their manufacturer to finally solve this problem (apparently existing for years), then I would be a happy HepatoPro user again. I wonder that there are not much more complaints, I think these are no isolated incidents.

Right, the liquid PhosChol would be an alternative but I hesitate to order from the US due to possible customs issues (I'm from the EU).

Bernhard


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 Posted 10/19/2013 6:59:40 AM
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I keep continuning the interaction with LEF. They asked to provide the lot no. which I did. They seem appreciating the problem and  will contact their Quality Assurance Department. I will post here their reply.

I am taking this product since long and always had the same problem. I would like to understand the underlying cause and be re insured there is no quality issue. I am not sure this an issue due to leaking capsules. That should appear in one bottle not always. I did have leaking softgel caps for other supplements which got replaced or reimbursed.
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